One Health Virology

The evolving trend of viral outbreaks of the years has brought to fore the concept of One Health Virology. One Health is an approach that recognizes that the health of people is connected to the health of animals and the environment. As human populations grow and expand into the ecosystems of wild animals, the potential for zoonotic viral outbreaks tends to increase. Close contact with wild and domestic animals provides opportunity for virus transmission. This transmission is further enhanced by deforestation, intensive farming practices, degradation of lands, mining activities and lifestyle behaviors. One Health Virology attempts to create common platform for addressing viral pandemics through cross-interactions with veterinary medicine, human medicine, biomedical science, Agricultural departments, environmental agencies and social scientists. The research interests of the One Health virology group includes conducting surveillance for detecting epidemic prone viral agents of public health importance, investigating the potential sources and reservoirs of viruses and controlling viral pandemic through public engagements and educational programmes. We collaborate strongly with the Public Health Division of the Ghana Health Service, The Veterinary Services Department, Ministry of Food and Agriculture and Ministry of Health.

Funded Projects

The influence of diagnostics of specific viral etiological agents of encephalitis on outcome of disease

The potential of nonhuman primates as a reservoir for human yaws (TREPS)

SORMAS goes One Health: Water-based Outbreak Prediction in Peri-Urban Africa (SORMAS-WOPPA)

Spectrum Of Respiratory Pathogens Circulating In COVID-19 Suspected Clinical Cases In Ghana (RESPONSE)

Training & Monitoring antibody responses following vaccination against SARS-CoV-2 In Ghana

Serum antibody neutralization titres against Wuhan, Delta and Omicron at baseline and post 2nd dose

Diagnosing Tuberculosis in West Africa to inform immediate drug choice and save lives (MRC IAA)

Collection of epidemiological data and selective examination of immunity to predict future pandemics in Ghana.


We have supported the Ghana Health Service and Ministry of Health in conducting surveillance of SARS-CoV-2, Monkeypox viruses and Influenza viruses. We serve about 12 of the 16 regions in Ghana and have played active role in responding to major outbreaks in these regions. Our laboratory conducts routine testing for suspected individuals in these regions and provided real-time results to the Public Health Division of the Ghana Health Service to aid interventions in controlling outbreaks and management of pandemics. Since the first detections of COVID-19 in Ghana, our group has conducted over 200,000 tests mostly in the northern part of Ghana. Our group also tested sand continues to test several suspected samples for monkeypox and influenza A.
Training and Capacity Building
Our Senior Research fellows have supported training of several laboratories in molecular detection of viruses using molecular diagnostic platforms. We have set up about 15 laboratories and trained over 100 laboratory scientists in the northern part of Ghana. Our training ranges from onsite and off-site theory to hands-on bench training in the rudiments of viral testing and quality control procedures. Our trainees are manning a number of laboratories in many laboratories and continue to receive mentorship support from our team of experts.

Training and Capacity Building

Our Senior Research fellows have supported training of several laboratories in molecular detection of viruses using molecular diagnostic platforms. We have set up about 15 laboratories and trained over 100 laboratory scientists in the northern part of Ghana. Our training ranges from onsite and off-site theory to hands-on bench training in the rudiments of viral testing and quality control procedures. Our trainees are manning a number of laboratories in many laboratories and continue to receive mentorship support from our team of experts. 

Education and Media Engagements

Our group is not only focused on bench training but has continuously engaged the general public through the print and electronic media. We have provided training on preventive measures of COVID-19, supported vaccination drive and explained the origins of viral pandemics and outbreaks to the general public. We have also provided advise to government agencies and Ministry of Health on decision the country needed to take in the early days of COVID-19 outbreaks.

Links to media engagements

COVID vaccine: What’s at stake for Africa? – Alliance for Science

Ministry of Information – The Key Points – 18/04/2020

TV3 News Live – The Key Points – 11/04/20

Virologist calls for stronger surveillance measures to prevent escalation of cases. – JoyNews

COVID-19, The Ghana Story so far by the KNUST Academics – myjoyonline

KCCR researcher warns of possible COVID-19 cases surge after easing of restrictions – Citi Newsroom

Confronting future viruses head-on: Invest in research – institutions challenge nation – Graphic Online

Surge In COVID-19 Cases Might Be As Result Of Temperature Ranges- Dr. Michael Owusu – Peacefm Online

COVID-19 Pandemic: Assessing Ghana’s case count and peak status – UPfront on Joy News (6-5-20) 


Lockdown Helps Cut The Viral Growth Of COVID-19 – Dr. Michael Owusu – Peacefm Online

Africa’s vaccine rollout lags as COVID-19 deaths spike – Alliance for Science

Charité – Universitätsmedizin Berlin

Ghana Health Service

Ghana Ministry of Health

Other Partners

Veterinary Service Department

  1. The influence of diagnostics of specific viral etiological agents of encephalitis on outcome of disease.

     Funder: European and Developing Countries Clinical Trials Partnership (EDCTP).

     Project Period: 01 March 2018 – 28 February 2022


  1. The potential of nonhuman primates as a reservoir for human yaws (TREPS).

      Funder: German Research Foundation (DFG).

      Project Period:  01 September 2018 -31 August 2024


  1. SORMAS goes One Health: Water-based Outbreak Prediction in Peri-Urban Africa (SORMAS-WOPPA)

Funder: Friedrich-Loeffler-Institute (FLI).

Project Period:  01 January 2021 – 31 December 2023


  1. Spectrum of Respiratory Pathogens Circulating in COVID-19 Suspected Clinical Cases in Ghana (RESPONSE).

Funder: Government of Ghana, Ministry of Health.

Project Period: January 2022-December 2023


  1. Training & monitoring antibody following vaccination against SARS-CoV-2 in Ghana.

Funder: World Bank & Government of Ghana through Ministry of Health.

Project Period: November 2021-December 2022


  1. Diagnosing Tuberculosis in West Africa to inform immediate drug choice and save lives

Funder: MRC IAA University of Surrey

Project Period: July 2022 – January 2023

    1. Blood collection tubes impact expression of activated CD4+ and CD8+ T cells in human whole blood assay. Alexander Kwarteng, Priscilla Osei-Poku, Daniel Antwi-Berko, Augustina Sylverken, Amma Larbi, Kwabena Nsiah. Scientific African, 2023, e01797


    1. Antimicrobial activities of Hibiscus sabdariffa and Aspilia africana against clinical isolates of Salmonella typhi. Gadafi Iddrisu Balali, Denis Dekugmen Yar, Augustina Angelina Sylverken. Scientific African, 2023; 20: e01667


    1. Strengthening existing surveillance platforms to monitor pandemic-prone pathogens. Augustina Angelina Sylverken. The Lancet Global Health, 2023; 11(7): e993-e994


    1. Effects of COVID-19 disease on PAI-1 antigen and haematological parameters during disease management: A prospective cross-sectional study in a regional Hospital in Ghana. Charles Nkansah, Michael Owusu, Samuel Kwasi Appiah, Kofi Mensah, Simon Bannison Bani, Felix Osei-Boakye, Lawrence Duah Agyemang, Ezekiel Bonwin Ackah, Gabriel Abbam, Samira Daud, Yeduah Quansah, Charles Angnataa Derigubah, Francis Atoroba Apodola, Valentine Ayangba, David Amoah Afrifa, Caleb Paul Eshun, Abdul-Waliu Iddrisu, Selina Mintaah, Benjamin Twum, Abidatu Mohammed, Eugene Mensah Agyare, Wendy Akomeah Gyasi, Peace Esenam Agbadza, Candy Adwoa Ewusiwaa Wilson, Seth Anane, Prince Antwi, Reginald Akwasi Yeboah Antw Plos Global Public Health. 2023 Jun 22; 3(6): e0001866


    1. Solid waste motor tricycle operators in Kumasi, Ghana, harbour respiratory pathogens; a public health threat. Stephen Yaw Armoh, Sherihane Aryeetey, Japhet Senyo Kamasah, Kennedy Gyau Boahen, Michael Owusu, Augustina Adjei-Boateng, Olivia Agbenyega, Alexander Kwarteng, Suzanne Hingley-Wilson, Kwasi Obiri-Danso, Daniel Ansong, Augustina Angelina Sylverken. Plos one. 2023 Apr 24; 18(4): e0284985


    1. A multiplex PCR assay for the differentiation of Mycobacterium tuberculosiscomplex reveals high rates of mixed-lineage tuberculosis infections among patients in Ghana. Wellington Owusu, Arnoud H. M. van Vliet, Natalie E. Riddell, Graham Stewart, Winifred C. Akwani, Sherihane Aryeetey, Rejoice Agyeiwaa Arthur, Augustina Angelina Sylverken, Suzanne M. Hingley-Wilson. Frontiers in Cellular and infection Microbiology. 2023 Apr 3; 13: 354


    1. Antibiotic resistance and mecA characterization of Staphylococcus hominisfrom filarial lymphedema patients in the Ahanta West District, Ghana: A cross‐sectional  Priscilla Kini, Solomon Wireko, Priscilla Osei‐Poku, Samuel O Asiedu, Emmanuel KA Amewu, Ebenezer Asiedu, Ernest Amanor, Caleb Mensah, Mary B Wilson, Amma Larbi, Kennedy G Boahen, Augustina A Sylverken, Katherine R Amato, Alexander Kwarteng. Health Science Reports, 2023; 6(2): e1104


    1. No evidence for yaws infection in a small‐scale cross‐sectional serosurvey in Ghanaian monkeys. Eugene Adade, Christian Roos, Idrissa Shomari Chuma, Augustina Angelina Sylverken, Sascha Knauf. Veterinary Medicine and Science, 2023; 9(1): 507-512


    1. RETRACTED: Gradual emergence followed by exponential spread of the SARS-CoV-2 Omicron variant in Africa. Carlo Fischer, Tongai Gibson Maponga, Anges Yadouleton, Nuro Abilio, Emmanuel Aboce, Priase Adewumi, Pedro Afonso, Jewelina Akorli, Soa Fy Andriamandimby, Latifa Anga, Yvonne Ashong, Mohamed Amine Beloufa, Aicha Bensalme, Richad Birtles, Anicet Luc Magloire Boumba, Freddie Bwanga, Mike Chaponda, Paradzai Chibukira, R. Matthew Chico, Justin Chileshe, Gershom Chongwe, Assana Cissé, Umberto D’Alessandro, Xavier Nicolas de Lamballerie, Joana F. M. de Morais, Fawzi Derrar, Ndongo Dia, Youssouf Diarra, Lassina Doumbia, Christen Drosen, Philippe Dussart, Richard Echodu, Yannik Eggers, Abdelmajid Eloualid, Ousmane Faye, Torsten Feldt, Anna Frühauf, Afiwa Halatoko, Pauliana-Vanessa Ilouga, Nalia Ismael, Ronan Jambou, Sheikh Jarju, Antje Kamprad, Ben Katowa, John Kayiwa, Leonard King’wara, Ousmane Koita, Vincent Lacoste, Adamou Lagare, Olfert Landt, Sonia Etenna Lekana-Douki, Jean-Bernard Lekana-Douki, Etuhole Iipumbu, Hugues Loemba, Julius Lutwama, Santou Mamadou, Issaka Maman, Brendon Manyisa, Pedro A. Martinez, Japhet Matoba, Lusia Mhuulu, Andres Moreira-Soto, Judy Mwangi, Nadine N´dilimabaka, Charity Angella Nassuna, Mamadou Ousmane Ndiath, Emmanuel Nepolo, Richard Njouom, Jalal Nourlil, Steven Ger Nyanjom, Eddy Okoth Odari, Alfred Okeng, Jean Bienvenue Ouoba, Michael Owusu, Irene Owusu Donkor, Karabo Kristen Phadu, Richard Odame Phillips, Wolfgang Preiser, Vurayai Ruhanya, Fortune Salah, Sourakatou Salifou, Amadou Alpha Sall, Augustina Angelina Sylverken, Paul Alain Tagnouokam-Ngoupo, Zekiba Tarnagda, Francis Olivier Tchikaya, Tafese Beyene Tufa, Jan Felix Drexler. Science, 2022, Vol 378, Issue 6623, DOI: 1126/science.add8737


    1. Using drones to transport suspected COVID-19 samples; experiences from the second largest testing centre in Ghana, West Africa. Augustina Angelina Sylverken, Michael Owusu, Bernadette Agbavor, Alex Kwarteng, Nana Kwame Ayisi-Boateng, Patrick Ofori, Philip El-Duah, Richmond Yeboah, Sherihane Aryeetey, Jesse Addo Asamoah, Rita Ziem Ekekpi, Morrah Oppong, Richmond Gorman, Kofi Adjei Brempong, Emmanuella Nyarko-Afriyie, Felix Owusu Bonsu, Rita Larsen-Reindorf, Michael Rockson Adjei, Gifty Boateng, Franklin Asiedu-Bekoe, Badu Sarkodie, Dennis O. Laryea, Emmanuel Tinkorang, Patrick Kumah Aboagye, Anthony Nsiah Asare, Kwasi Obiri-Danso, Ellis Owusu-Dabo, Yaw Adu-Sarkodie, Richard Odame Phillips. Plos one. 2022 Nov 1; 17(11): e0277057


    1. SARS-COV-2 antibody responses to AZD1222 vaccination in West Africa. Adam Abdullahi, David Oladele, Michael Owusu, Steven A. Kemp, James Ayorinde, Abideen Salako, Douglas Fink, Fehintola Ige, Isabella A. T. M. Ferreira, Bo Meng, Augustina Angelina Sylverken, Chika Onwuamah, Kwame Ofori Boadu, Kazeem Osuolale, James Opoku Frimpong, Rufai Abubakar, Azuka Okuruawe, Haruna Wisso Abdullahi, Gideon Liboro, Lawrence Duah Agyemang, Nana Kwame Ayisi-Boateng, Oluwatosin Odubela, Gregory Ohihoin, Oliver Ezechi, Japhet Senyo Kamasah, Emmanuel Ameyaw, Joshua Arthur, Derrick Boakye Kyei, Dorcas Ohui Owusu, Olagoke Usman, Sunday Mogaji, Adedamola Dada, George Agyei, Soraya Ebrahimi, Lourdes Ceron Gutierrez, Sani H. Aliyu, Rainer Doffinger, Rosemary Audu, Richard Adegbola, Petra Mlcochova, Richard Odame Phillips, Babatunde Lawal Solako, Ravindra K. Gupta. Nature Communications. 2022 Oct 17; 13(1): 6131. 1038/s41467-022-33792-x


    1. Clinical profile and predictors of viral suppression in HIV-infected older adults at a University Hospital in Kumasi, Ghana. Nana Kwame Ayisi-Boateng, Douglas Aninng Opoku, Isaac Nkrumah, Bernard Frempong, Michael Owusu, Eric Oduro, Brenda Abena Ampah, Emmanuel Konadu, Betty Norman. AIDS care. 2022 Sep 17; 1-9. DOI: 1080/09540121.2022.2119468.


    1. COVID-19 and Burkholderia cepacian co-infection in pregnancy associated with fetal demise: a case report. Brenda Abena Ampah, Nana Kwame Ayisi-Boateng, Augustina Angelina Sylverken, Japhet Senyo, Kennedy Gyau, Betty Nkansah Osei Mensah, Godfred Acheampong, Michael Owusu. Pan African Medical Journal, 2022; 42: 173. 10.11604/pamj.2022.42.173.33813


    1. Genetic characterization of varicella-zoster and HIV-1 viruses from the cerebrospinal fluid of a co-infected encephalitic patient, Ghana. Philip El-Duah, Augustina Angelina SylverkenMichael Owusu, Yaw Ampem Amoako, Richmond Yeboah, Richmond Gorman, Emmanuella Nyarko-Afriyie, Julia Schneider, Terry C. Jones, Joseph Bonney, Titus Adade, Eric Smart Yeboah, Tabea Binger, Victor Max Corman, Christian Drosten, Richard Odame Phillips. Virology journal. 2022 Jul 26; 19(1): 122
    1. Comparable detection of SARS-CoV-2 in sputum and oropharyngeal swab samples of suspected COVID-19 patients. Emmanuel Akowuah, Godfred Acheampong, Nana Kwame Ayisi-Boateng, Andrews Amaniampong, Francis Opoku Agyapong, Japhet Senyo Kamasah, George Agyei, Dorcas Ohui Owusu, Bernard Nkrumah, Mohamed Mutocheluh, Augustina Angelina Sylverken, Michael Owusu. COVID. 2022 Jun 24; 2(7); 858-66. 3390/covid2070062


    1. User experiences of a mobile phone-based health information and surveillance system (mHISS): A case of caregivers of children under-five in rural communities in Ghana. Acquah-Gyan Emmanuel, Acheampong Princess Ruhama, Mohammed Aliyu, Adjei Timothy Kwabena, Agyapong Emmanuel, Twumasi-Ankrah Sampson, Sylverken Augustina, Owusu Michael, Owusu-Dabo Ellis. Plos one, 2022, Vol 17, Issue 1, e0261806.


    1. The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance. Houriiyah Tegally, James E San, Matthew Cotten, Monika Moir, Bryan Tegomoh, Gerald Mboowa, Darren P Martin, Cheryl Baxter, Arnold W Lambisia, Amadou Diallo, Daniel G Amoako, Moussa M Diagne, Abay Sisay, Abdel-Rahman N Zekri, Abdou Salam Gueye, Abdoul K Sangare, Abdoul-Salam Ouedraogo, Abdourahmane Sow, Abdualmoniem O Musa, Abdul K Sesay, Abe G Abias, Adam I Elzagheid, Adamou Lagare, Adedotun-Sulaiman Kemi, Aden Elmi Abar, Adeniji A Johnson, Adeola Fowotade, Adeyemi O Oluwapelumi, Adrienne A Amuri, Agnes Juru, Ahmed Kandeil, Ahmed Mostafa, Ahmed Rebai, Ahmed Sayed, Akano Kazeem, Aladje Balde, Alan Christoffels, Alexander J Trotter, Allan Campbell, Alpha K Keita, Amadou Kone, Amal Bouzid, Amal Souissi, Ambrose Agweyu, Amel Naguib, Ana V Gutierrez, Anatole Nkeshimana, Andrew J Page, Anges Yadouleton, Anika Vinze, Anise N Happi, Anissa Chouikha, Arash Iranzadeh, Arisha Maharaj, Armel L Batchi-Bouyou, Arshad Ismail, Augustina A Sylverken, Augustine Goba, Ayoade Femi, Ayotunde E Sijuwola, Baba Marycelin, Babatunde L Salako, Bamidele S Oderinde, Bankole Bolajoko, Bassirou Diarra, Belinda L Herring, Benjamin Tsofa, Bernard Lekana-Douki, Bernard Mvula, Berthe-Marie Njanpop-Lafourcade, Blessing T Marondera, Bouh Abdi Khaireh, Bourema Kouriba, Bright Adu, Brigitte Pool, Bronwyn McInnis, Cara Brook, Carolyn Williamson, Cassien Nduwimana, Catherine Anscombe, Catherine B Pratt, Cathrine Scheepers, Chantal G Akoua-Koffi, Charles N Agoti, Chastel M Mapanguy, Cheikh Loucoubar, Chika K Onwuamah, Chikwe Ihekweazu, Christian N Malaka, Christophe Peyrefitte, Chukwa Grace, Chukwuma E Omoruyi, Clotaire D Rafaï, Collins M Morang’a, Cyril Erameh, Daniel B Lule, Daniel J Bridges, Daniel Mukadi-Bamuleka, Danny Park, David A Rasmussen, David Baker, David J Nokes, Deogratius Ssemwanga, Derek Tshiabuila, Dominic SY Amuzu, Dominique Goedhals, Donald S Grant, Donwilliams O Omuoyo, Dorcas Maruapula, Dorcas W Wanjohi, Ebenezer Foster-Nyarko, Eddy K Lusamaki, Edgar Simulundu, Edidah M Ong’era, Edith N Ngabana, Edward O Abworo, Edward Otieno, Edwin Shumba, Edwine Barasa, El Bara Ahmed, Elhadi A Ahmed, Emmanuel Lokilo, Enatha Mukantwari, Eromon Philomena, Essia Belarbi, Etienne Simon-Loriere, Etilé A Anoh, Eusebio Manuel, Fabian Leendertz, Fahn M Taweh, Fares Wasfi, Fatma Abdelmoula, Faustinos T Takawira, Fawzi Derrar, Fehintola V Ajogbasile, Florette Treurnicht, Folarin Onikepe, Francine Ntoumi, Francisca M Muyembe, Frank EZ Ragomzingba, Fred A Dratibi, Fred-Akintunwa Iyanu, Gabriel K Mbunsu, Gaetan Thilliez, Gemma L Kay, George O Akpede, Gert U van Zyl, Gordon A Awandare, Grace S Kpeli, Grit Schubert. Science, 2022, 378 (6615), eabq5358


    1. Effect of pulmonary tuberculosis on natural anticoagulant activity in therapy-naïve Ghanaian adults; a case-control study. Osei-Boakye Felix, Addai-Mensah Otchere, Owusu Michael, Saasi Abdul-Razak, Appiah Samuel Kwasi, Nkansah Charles, Wiafe Yaw Amo, Debrah Alexander Yaw. Journal of Immunoassay and Immunochemistry, 2022, 17-Jan.


    1. Surveillance and laboratory collaboration in response to an outbreak of Vibrio parahaemolyticus, Plesiomonas shigelloides, and Aeromonas hydrophila in Sekondi-Takoradi, Ghana: a case series. Owusu Michael, Nkrumah Bernard, Mensah Ebenezer Kofi, Lamptey Jones, Acheampong Godfred, Sambian David, Sylverken Augustina, Emery Shannon, Robinson Lucy Maryogo, Sefa Solomon Asante. Journal of Medical Case Reports, 2022, Vol 16, Issue 1, 5-Jan.


    1. What Is in the Salad? Escherichia coliand Antibiotic Resistance in Lettuce Irrigated with Various Water Sources in Ghana. Gerard Quarcoo, Lady A Boamah Adomako, Arpine Abrahamyan, Samuel Armoo, Augustina A Sylverken, Matthew Glover Addo, Sevak Alaverdyan, Nasreen S Jessani, Anthony D Harries, Hawa Ahmed, Regina A Banu, Selorm Borbor, Mark O Akrong, Nana A Amonoo, Emmanuel MO Bekoe, Mike Y Osei-Atweneboana, Rony Zachariah. International Journal of Environmental Research and Public Health, 2022; 19(19): 12722


    1. Bacterial diversity significantly reduces toward the late stages among filarial lymphedema patients in the Ahanta West District of Ghana: a cross‐sectional study. Samuel O Asiedu, Priscilla Kini, Bill C Aglomasa, Emmanuel KA Amewu, Ebenezer Asiedu, Solomon Wireko, Kennedy G Boahen, Afiat Berbudi, Augustina A Sylverken, Alexander Kwarteng. Health Science Reports, 2022; 5(4): e724


    1. Low risk of SARS-CoV-2 in blood transfusion. Michael Owusu, Augustina Angelina Sylverken, Philip El-Duah, Nana Kwame Ayisi-Boateng, Richmond Yeboah, Eric Adu, Jesse Asamoah, Michael Frimpong, Japhet Senyo, Godfred Acheampong, Mohamed Mutocheluh, John Amuasi, Ellis Owusu-Dabo, Yaw Adu-Sarkodie, Richard Odame Phillips. Plos one, 2021, Vol 16, Issue 4, e0249069.


    1. Transmission of SARS-CoV-2 in northern Ghana: insights from whole-genome sequencing. Augustina Angelina Sylverken, Philip El-Duah, Michael Owusu, Julia Schneider, Richmond Yeboah, Nana Kwame Ayisi-Boateng, Richmond Gorman, Eric Adu, Alexander Kwarteng, Michael Frimpong, Tabea Binger, Sherihane Aryeetey, Jesse Addo Asamoah, Yaw Ampem Amoako, John Humphrey Amuasi, Jörn Beheim-Schwarzbach, Ellis Owusu-Dabo, Yaw Adu-Sarkodie, Kwasi Obiri-Danso, Victor Max Corman, Christian Drosten, Richard Phillips. Archives of virology, 2021, Vol 166, Issue 5, Pages 1385 – 1393.


    1. Genomic and epidemiological characteristics of SARS-CoV-2 in Africa. Jones Lamptey, Favour Oluwapelumi Oyelami, Michael Owusu, Bernard Nkrumah, Paul Oluwagbenga Idowu, Enoch Appiah Adu-Gyamfi, Armin Czika, Philip El-Duah, Richmond Yeboah, Augustina Sylverken, Oluwatayo Israel Olasunkanmi, Ellis Owusu-Dabo, Christian Drosten, Yaw Adu-Sarkodie. PLOS Neglected Tropical Diseases, 2021, Vol 15, Issue 4, Pages e0009335.


    1. A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa. Wilkinson Eduan, Giovanetti Marta, Tegally Houriiyah, San James E, Lessells Richard, Cuadros Diego, Martin Darren P, Rasmussen David A, Zekri Abdel-Rahman N, Sangare Abdoul K. Science, 2021, Vol 374, Issue 6566, Pages 423-431.


    1. Sero-epidemiology of human coronaviruses in three rural communities in Ghana. Owusu Michael, Sylverken Augustina Angelina, El-Duah Philip, Acheampong Godfred, Mutocheluh Mohammed, Adu-Sarkodie Yaw. The Pan African Medical Journal, 2021, Vol 38.


    1. The burden of drug resistance tuberculosis in Ghana; results of the First National Survey. Sylverken Augustina Angelina, Kwarteng Alexander, Twumasi-Ankrah Sampson, Owusu Michael, Arthur Rejoice Agyeiwaa, Dumevi Rexford Mawunyo, Adu-Amoah Louis, Addofoh Nicholas, Okyere Portia Boakye, Dzata Francisca. PloS one, 2021, Vol 16, Issue 6, e0252819.


    1. Sero-molecular epidemiology of hepatitis E virus in pigs and human contacts in Ghana. Yeboah Richmond, Sylverken Augustina Angelina, Owusu Michael, El-Duah Philip, Burimuah Vitus, Frimpong Yaw, Lamptey Jones, Eckerle Isabella, Meyer Benjamin, Antwi Christopher. One Health Outlook, 2021, Vol 3, Issue 1, 11-Jan.


    1. SARS-CoV-2 viral shedding and transmission dynamics: implications of WHO COVID-19 discharge guidelines. Kingsley Badu, Kolapo Oyebola, Julien ZB Zahouli, Adeniyi Francis Fagbamigbe, Dziedzom K de Souza, Natisha Dukhi, Ebenezer F Amankwaa, Mai F Tolba, Augustina A Sylverken, Lydia Mosi, Priscilla Kolibea Mante, Damaris Matoke-Muhia, Nowsheen Goonoo. Frontiers in Medicine, 2021, Vol 8, 64860


    1. At least seven distinct rotavirus genotype constellations in bats with evidence of reassortment and zoonotic transmissions. Ceren Simsek, Victor Max Corman, Hermann Ulrich Everling, Alexander N Lukashev, Andrea Rasche, Gael Darren Maganga, Tabea Binger, Daan Jansen, Leen Beller, Ward Deboutte, Florian Gloza-Rausch, Antje Seebens-Hoyer, Stoian Yordanov, Augustina Sylverken, Samuel Oppong, Yaw Adu Sarkodie, Peter Vallo, Eric M Leroy, Mathieu Bourgarel, Kwe Claude Yinda, Marc Van Ranst, Christian Drosten, Jan Felix Drexler, Jelle Matthijnssens. MBio, 2021, 12 (1), 10.1128/mbio.02755-20


    1. Antimicrobial resistance of Escherichia coli from broilers, pigs, and cattle in the greater kumasi metropolis, Ghana. Rita Ohene Larbi, Linda Aurelia Ofori, Augustina Angelina Sylverken, Matilda Ayim-Akonor, Kwasi Obiri-Danso. International Journal of Microbiology, 2021; 2021: 1-7


    1. Molecular characterization of interactions between the D614G variant of SARS-CoV-2 S-protein and neutralizing antibodies: a computational approach. Alexander Kwarteng, Ebenezer Asiedu, Augustina Angelina Sylverken, Amma Larbi, Samuel Asamoah Sakyi, Samuel Opoku Asiedu. Infection, Genetics and Evolution, 2021; 91: 104815


    1. Correlating WHO COVID-19 interim guideline 2020.5 and testing capacity, accuracy, and logistical challenges in Africa. Lydia Mosi, Augustina Angelina Sylverken, Kolapo Oyebola, Kingsley Badu, Natisha Dukhi, Nowsheen Goonoo, Priscilla Kolibea Mante, Julien Zahouli, Ebenezer Forkuo Amankwaa, Mai Fathy Tolba, Adeniyi Francis Fagbamigbe, Dziedzom Komi de Souza, Damaris Matoke-Muhia. 2021


    1. Microbial Load and Antibiotic Resistance of Escherichia coliand Staphylococcus aureus Isolated from Ready-to-Eat (RTE) Khebab Sold on a University Campus and Its Environs in Ghana. Azumah Ayamah, Augustina Angelina Sylverken, Linda Aurelia Ofor Journal of Food Quality. 2021 Dec 29; 2021: 1-9


    1. Genome editing as control tool for filarial infections. Alexander Kwarteng, Augustina Sylverken, Ebenezer Asiedu, Samuel Terkper Ahuno. Biomedicine & Pharmacotherapy, 2021; 137: 111292


    1. Assessment of microbiological quality of khebab sold on the campus of a tertiary education and its environs in Ghana. Azumah Ayamah, Augustina Angelina Sylverken, Linda Aurelia Andoh. Journal of Microbiology and Antimicrobials, 2021; 13(2): 20-26


    1. In silico drug repurposing for filarial infection predicts nilotinib and paritaprevir as potential inhibitors of the Wolbachia5′-aminolevulinic acid synthase. Alexander Kwarteng, Ebenezer Asiedu, Augustina Sylverken, Amma Larbi, Yusif Mubarik, Charles Apprey. Scientific Reports, 2021; 11(1): 8455


    1. Prospects of immunology education and research in developing countries. Alexander Kwarteng, Augustina Sylverken, Daniel Antwi-Berko, Samuel Terkper Ahuno, Samuel Opoku Asiedu. Frontiers in Public Health, 2021; 9: 652439


    1. Common bacteria in sputum or gastric lavage of patients presenting with signs and symptoms of lower respiratory tract infections. Deberu Oliver, Nkrumah Bernard, Sylverken Augustina Angelina, Sambian David, Acheampong Godfred, Amuasi John, Stebleson Azure, Agboyie Daron, Yenbaree Monica, Mensah Sylvester, Owusu M. The Pan African Medical Journal, 2021, Vol 38.


    1. Evidence of chikungunya virus infections among febrile patients at three secondary health facilities in the Ashanti and the Bono Regions of Ghana. Adusei Jonathan Akwasi, Narkwa Patrick Williams, Owusu Michael, Domfeh Seth Agyei, Alhassan Mahmood, Appau Emmanuel, Salam Alimatu, Mutocheluh Mohamed. PLoS neglected tropical diseases, 2021, Vol 15, Issue 8, e0009735.


    1. Microbiological profile of asymptomatic bacteriuria in pregnant women in Volta Region, Ghana. Ahiatrogah Dzifa Kofi, Annan Jude John, Ofori Linda Aurelia, Awudzi Benedict, Owusu-Ofori Alex, Owusu Michael, Sylverken Augustina Angelina. Journal of Microbiology and Antimicrobials, 2021, Journal of Microbiology and Antimicrobials, Vol 13, Issue 2, Pages 27-36.


    1. Performance of COVID-19 associated symptoms and temperature checking as a screening tool for SARS-CoV-2 infection. Nuertey Benjamin Demah, Ekremet Kwame, Haidallah Abdul-Rashid, Mumuni Kareem, Addai Joyce, Attibu Rosemary Ivy E, Damah Michael C, Duorinaa Elvis, Seidu Anwar Sadat, Adongo Victor C, Michael Owusu, Augustinna Sylveken, Richard Phillips. PloS one, 2021, Vol 16, Issue 9, e0257450.


    1. Estimating the incidence of typhoidal Salmonella from cross-sectional serology using antibody dynamics following infection. Aiemjoy Kristen, Seidman Jessica C, Saha Senjuti, Munira Sira Jam, Sajib Mohammad Saiful Islam, Al Sium Syed Muktadir, Sarkar Anik, Alam Nusrat, Jahan Farha Nusrat, Kabir Md Shakiul, Michael Owusu et al medRxiv, 2021.


    1. Rabies is still a fatal but neglected disease: a case report. Amoako YA, El-Duah P, Sylverken AA, Owusu M, Yeboah R, Gorman R, Adade T, Bonney J, Tasiame W, Nyarko-Jectey K. Journal of Medical Case Reports, 2021, Vol 15, Issue 1, 6-Jan.


    1. Incidence of non-typhoidal Salmonella invasive disease: A systematic review and meta-analysis. Christian S Marchello, Fabio Fiorino, Elena Pettini, John A Crump, Laura B Martin, Gianluca Breghi, Rocio Canals, Melita A Gordon, Brama Hanumunthadu, Jan Jacobs, Samuel Kariuki, Jong-Hoon Kim, Stefano Malvolti, Carsten Mantel, Florian Marks, Donata Medaglini, Vittal Mogasale, Esther Muthumbi, Robert Onsare, Ellis Owusu-Dabo, Michael Owusu, Tonney Niyrenda, Maheshi Ramasamy, J Anthony Scott, Bassiahi Abdramane Soura, Tiziana Spadafina, Bieke Tack. Journal of Infection, 2021, Vol 83, Issue 5, Pages 523-532.


    1. Forecasting COVID-19 Confirmed Cases in Ghana: A Model Selection Approach. Twumasi-Ankrah Sampson, Owusu Michael, Appiah Simon Kojo, Pels Wilhemina Adoma, Arthur Doris. Traektoriâ Nauki. Path of Science, 2021, Vol 7, Issue 2, Pages 4001-4010.


    1. Determinants of a mobile phone-based Interactive Voice Response (mIVR) system for monitoring childhood illnesses in a rural district of Ghana: Empirical evidence from the UTAUT model. Adjei Timothy Kwabena, Mohammed Aliyu, Acheampong Princess Ruhama, Acquah-Gyan Emmanuel, Sylverken Augustina, Twumasi-Ankrah Sampson, Owusu Michael, Owusu-Dabo Ellis. PloS one, 2021, Vol 16, Issue 3, e0248363.


    1. Evaluation of Typhoid Conjugate Vaccine Effectiveness in Ghana (TyVEGHA) Using a Cluster-Randomized Controlled Phase IV Trial: Trial Design and Population Baseline Characteristics. Haselbeck Andrea Haekyung, Tadesse Birkneh Tilahun, Park Juyeon, Gibani Malick M, Espinoza Ligia María Cruz, Abreu Ariane, Van Rensburg Craig, Owusu-Ansah Michael, Twuamsi-Ankrah Sampson, Owusu Michael. Vaccines, 2021, Vol 9, Issue 3, Pages 281.


    1. Improved detection of microbiological pathogens: role of partner and non-governmental organizations. Owusu Michael, Nkrumah Bernard, Acheampong Godfred, Mensah Ebenezer Kofi, Komei Abass Abdul-Karim, Sroda Festus Kofi, David Sambian, Emery Shannon, Robinson Lucy Maryogo, Asante Kwame. BMC Infectious Diseases, 2021, Vol 21, Issue 1, 13-Jan.


    1. Plasminogen Activator Inhibitor-1 in poorly controlled vs well controlled Type-2 Diabetes Mellitus patients: A case-control study in a district hospital in Ghana. Nkansah Charles, Addai-Mensah Otchere, Mensah Kofi, Owusu Michael, Ephraim Richard KD, Adu Patrick, Osei-Boakye Felix, Appiah Samuel K, Serwaa Dorcas, Derigubah Charles A. PloS one, 2021, Vol 16, Issue 4, e0250090.


    1. Laboratory capacity in COVID-19 diagnosis and the need to enhance molecular testing in Ghana. Godfred Acheampong, Michael Owusu, Bernard Nkrumah, Priscilla Obeng-Boadi, David A Opare, David J Sambian, Pawan Angra, Chastity Walker. Global Security: Health, Science and Policy, 2021, Vol 6, Issue 1, Pages 10-17.


    1. Profile and outcomes of hospitalized patients with COVID-19 at a tertiary institution hospital in Ghana. Nana K Ayisi-Boateng, Michael Owusu, Phyllis Tawiah, Brenda A Ampah, Augustina A Sylverken, Osei K Wusu-Ansah, Fred S Sarfo, Richard O Phillips. Ghana Medical Journal, 2020, Vol 54, Issue 4s, Page 39-45.


    1. Diagnostics for COVID-19: A case for field-deployable, rapid molecular tests for community surveillance. Michael Frimpong, Yaw A Amoako, Kwadwo B Anim, Hubert S Ahor, Richmond Yeboah, Joshua Arthur, Justin S Dakorah, Delphine Gborgblovor, Samuel Akrofi, Phyllis Sekyi-Djan, Michael Owusu, Augustina A Sylverken, Tabea Binger, Richard O Phillips. Ghana Medical Journal, 2020, Vol 54, Issue 4s, Page 71-76.


    1. Epidemiological profile of SARS-CoV-2 among selected regions in Ghana: A cross-sectional retrospective study. Michael Owusu, Augustina Angelina Sylverken, Sampson Twumasi Ankrah, Philip El-Duah, Nana Kwame Ayisi-Boateng, Richmond Yeboah, Richmond Gorman, Jesse Asamoah, Tabea Binger, Godfred Acheampong, Franklin Asiedu Bekoe, Sally-Ann Ohene, Rita Larsen-Reindorf, Anthony Afum-Adjei Awuah, John Amuasi, Ellis Owusu-Dabo, Yaw Adu-Sarkodie, Richard Odame Phillips. PloS one, 2020, Vol 15, Issue 12, Pages e0243711.1371/journal.pone.0243711


    1. Africa’s response to the COVID-19 pandemic: A review of the nature of the virus, impacts and implications for preparedness [version 1; peer review: 2 approved with reservations]. Kingsley Badu, Jessica PR Thorn, Nowsheen Goonoo, Natisha Dukhi, Adeniyi Francis Fagbamigbe, Benard W Kulohoma, Kolapo Oyebola, Sara I Abdelsalam, Wesley Doorsamy, Olawale Awe, Augustina Angelina Sylverken, Anthony Egeru, Jesse Gitaka. 2020


    1. Detection and genomic characterization of hepatitis E virus genotype 3 from pigs in Ghana, Africa. Philip El-Duah, Dickson Dei, Tabea Binger, Augustina Sylverken, Robert Wollny, William Tasiame, Samuel Oppong, Yaw Adu-Sarkodie, Benjamin Emikpe, Raphael Folitse, Jan Felix Drexler, Richard Phillips, Christian Drosten, Victor Max Corman. One Health Outlook, 2020; 2: 1-9


    1. Cardiovascular disease risk assessment among patients attending two cardiac clinics in the Ashanti Region of Ghana. Waindim Nyiambam, Augustina Sylverken, Isaac Owusu, Kwame Buabeng, Fred Boateng, Ellis Owusu-Dabo. Ghana Medical Journal, 2020; 54(3): 140-145


    1. Effect of Pulmonary Tuberculosis on Protein C, S, and Antithrombin-III among Therapy-naïve Ghanaian Adults; A Comparative Cross-Sectional Study. Osei-Boakye Felix, Addai-Mensah Otchere, Owusu Michael, Saasi Abdul-Razak, Appiah Samuel Kwasi, Nkansah Charles, Wiafe Yaw Amo, Debrah Alexander Yaw. 2020.


    1. Human defensins and Th-1 cytokines in hepatitis C viral infection. Dorcas Ohui Owusu, Michael Owusu, Bright Afriyie Owusu. Pan African Medical Journal Volume 37, Article 103, 29 Sep 2020 | 10.11604/pamj.2020.37.103.25211


    1. Increased levels of circulating IL-10 in persons recovered from hepatitis C virus (HCV) infection compared with persons with active HCV infection. Dorcas Ohui Owusu, Richard Phillips, Michael Owusu, Fred Stephen Sarfo and Margaret Frempong. BMC Research Notes volume 13, Article number: 472 (2020) Cite this article 220 Accesses.


    1. Molecular-based cross-species evaluation of bovine coronavirus infection in cattle, sheep and goats in Ghana. Vitus Burimuah, Augustina Sylverken, Michael Owusu, Philip El-Duah, Richmond Yeboah, Jones Lamptey, Yaw Oppong Frimpong, Olivia Agbenyega, Raphael Folitse, Ben Emikpe, William Tasiame, Eddie-Williams Owiredu, Samuel Oppong, Christopher Antwi, Yaw Adu-Sarkodie, Christian Drosten. BMC Veterinary Research, Vol 16, Issue 1, page 1-7.1186/s12917-020-02606-x


    1. Influenza outbreak among students in Ghana: a report from three time points. Sylverken Augustina Angelina, Owusu Michael, Yeboah Richmond, El-Duah Philip, Gorman Richmond, Bonney Joseph Kofi, Aryeetey Sherihane, Adu Eric, Amoako Yaw Ampem, Adade Titus. 2020.


    1. SARS-CoV-2 updates in a West African population and precautionary measures for sustaining quality antenatal care delivery. Morhe Emmanuel Komla Senanu, Anto Enoch Odame, Coall David Antony, Adua Eric, Debrah Alexander Yaw, Addai-Mensah Otchere, Owusu Michael, Owiredu William KBA, Obirikorang Christian, Asiamah Emmanuel Akomanin. Journal of Global Health, 2020, Vol 10, Issue 4.


    1. Sero-prevalence, cross-species infection and serological determinants of prevalence of Bovine Coronavirus in Cattle, Sheep and Goats in Ghana. Vitus Burimuah, Augustina Sylverken, Michael Owusu, PhilipEl-Duah, Richmond Yeboah Jones Lamptey, Yaw Oppong Frimpong, Olivia Agbenyegah, Raphael Folitse, WilliamTasiame, BenjaminEmikpe, Eddie Williams, Owiredu Samuel Oppong, YawAdu-Sarkodie, ChristianDrosten. Veterinary Microbiology, Volume 241, February 2020, 108544.


    1. Prevalence of attention deficit hyperactivity disorder among pupils in primary schools in Ghana. Ntiakoh-Ayipah Daniel, Dogbe Joslin Alexei, Opoku Maxwell Peprah, Twum Frank, Owusu Michael, Kumi Hammond, Afari Priscilla, Donnir Gordon. Journal of International Special Needs Education, 2020, Vol 23, Issue 2, Pages 69-78.


    1. Identification of multidrug-resistant salmonella plasmid variants using polymerase chain reaction (PCR) based replicon typing technique in Ghana. Ellis Owusu-Dabo, Godfred Acheampong, Michael Owusu, Alex Owusu-Ofori Isaac Osei, Nimako Sarpong, Se Eun Park, Florian Marks, Africa Health Agenda International Journal. 2019;1:6


    1. Chromosomal and plasmid-mediated fluoroquinolone resistance in human Salmonella enterica infection in Ghana. Acheampong G, Owusu M, Owusu-Ofori A, Osei I, Sarpong N, Sylverken A, Kung HJ, Cho ST, Kuo CH, Park SE, Marks F, Adu-Sarkodie Y, Owusu-Dabo E.BMC Infect Dis. 2019 Oct 28;19(1):898. doi: 10.1186/s12879-019-4522-1.PMID: 31660876


    1. The Severe Typhoid Fever in Africa Program: Study Design and Methodology to Assess Disease Severity, Host Immunity, and Carriage Associated with Invasive Salmonellosis. Park SE, Toy T, Cruz Espinoza LM, Panzner U, Mogeni OD, Im J, Poudyal N, Pak GD, Seo H, Chon Y, Schütt-Gerowitt H, Mogasale V, Ramani E, Dey A, Park JY, Kim JH, Seo HJ, Jeon HJ, Haselbeck A, Conway Roy K, MacWright W, Adu-Sarkodie Y, Owusu-Dabo E, Osei I, Owusu M, Rakotozandrindrainy R, Soura AB, Kabore LP, Teferi M, Okeke IN, Kehinde A, Popoola O, Jacobs J, Lunguya Metila O, Meyer CG, Crump JA, Elias S, Maclennan CA, Parry CM, Baker S, Mintz ED, Breiman RF, Clemens JD, Marks F.Clin Infect Dis. 2019 Oct 30;69(Suppl 6):S422-S434. doi: 10.1093/cid/ciz715.PMID: 31665779


    1. Influence of seasonal variation on reported filarial attacks among people living with lymphedema in Ghana. Alexander Kwarteng, Yarhands Dissou Arthur, John Kanyiri Yamba, Augustina A Sylverken, Priscilla Kini, Samuel Terkper Ahuno, Ellis Owusu-Dabo. BMC infectious diseases, 2019, 19, 1-7


    1. Implications of WHO COVID-19 interim guideline 2020.5 on the comprehensive care for infected persons in Africa Before, during and after clinical management of cases. Adeniyi Francis Fagbamigbe, Mai F Tolba, Ebenezer F Amankwaa, Priscilla Kolibea Mante, Augustina Angelina Sylverken, Julien ZB Zahouli, Nowsheen Goonoo, Lydia Mosi, Kolapo Oyebola, Damaris Matoke-Muhia, Dziedzom K de Souza, Kingsley Badu, Natisha Dukhi. Scientific African. 2019


    1. Burden of respiratory viral infections among inmates of a Ghanaian prison. Sylverken Augustina, El-Duah Philip, Owusu Michael, Yeboah Richmond, Kwarteng Alexander, Ofori Linda, Gorman Richmond, Obiri-Danso Kwasi, Owusu-Dabo Ellis, 2019.


    1. Ralstonia mannitolilytica sepsis: a case report. Owusu M, Acheampong G, Annan A, Marfo KS, Osei I, Amuasi J, Sarpong N, Im J, Mogeni OD, Chiang HY, Kuo CH, Jeon HJ, Panzner U, Park SE, Marks F, Owusu-Dabo E, Adu-Sarkodie Y.J Med Case Rep. 2019 Oct 26;13(1):318. doi: 10.1186/s13256-019-2235-0.PMID: 31653273


    1. Sero-prevalence of Hepatitis B and C viral co-infections among HIV-1 infected ART-naïve individuals in Kumasi, Ghana.Richard Boateng, Mohamed Mutocheluh, Albert Dompreh, Dorcas Obiri-Yeboah, Enoch Odame Anto, Michael Owusu, Patrick Williams Narkwa, April, 2019, PlosOne


    1. Potential Intermediate Hosts for Coronavirus Transmission: No Evidence of Clade 2c Coronaviruses in Domestic Livestock from Ghana. Philip El-Duah, Augustina Sylverken, Michael Owusu, Richmond Yeboah, Jones Lamptey, Yaw Oppong Frimpong, Vitus Burimuah, Christopher Antwi  Raphael Folitse, Olivia Agbenyega, Samuel Oppong Yaw Adu-Sarkodie. Med. Infect. Dis. 2019, 4(1), 34


    1. Development of a Whole-Virus ELISA for Serological Evaluation of Domestic Livestock as Possible Hosts of Human Coronavirus NL63. Philip El-Duah, Benjamin Meyer, Augustina Sylverken, Michael Owusu, Lina Theresa Gottula, Richmond Yeboah, Jones Lamptey, Yaw Oppong Frimpong, Vitus Burimuah, Raphael Folitse, Olivia Agbenyega, Samuel Oppong, Yaw Adu-Sarkodie, Christian Drosten. Viruses.2019;11:43


    1. Use of social media in a national Tuberculosis Drug Resistance Survey: lessons from the first anti-tuberculosis drug resistance survey in Ghana. Sylverken Augustina Angelina, Owusu-Dabo Ellis, Kwarteng Alexander, Twumasi-Ankrah Sampson, Owusu Michael, Adu-Amoah Louis, Dumevi Rexford Mawunyo, Arthur Rejoice Agyeiwaa, Addofoh Nicholas, Dzata Francisca. AAS Open Research, 2019, Vol 2, Pages 4.


    1. Gonococcal sepsis in a 32-year-old female: a case report. M Owusu, KS Marfo, G Acheampong, A Arthur, N Sarpong, J Im,BMC research notes 11 (1), 253:2018


    1. Key drivers of graduate students’ interest in the subject of immunology in a tertiary institution of Ghana. Alexander Kwarteng, Yarhands Dissou-Arthur, Augustina Sylverken, Michael Frimpong, Samuel Ahuno Terkper, Ellis Owusu-Dabo. Cogent Education, 2018; 5(1): 1498162


    1. Aetiology of viral hepatitis among jaundiced patients presenting to a tertiary hospital in Ghana. Owusu Michael, Bonney Joseph Kofi, Annan Augustina Angelina, Mawuli Gifty, Okyere Kennedy, Mutocheluh Mohamed, Aryeequaye Juliana, Adjei Nicholas Kwabena, Afihene Mary, Spangenberg Kathryn. PloS one, 2018, Vol 13, Issue 9, e0203699.


    1. Melioidosis in Africa: Time to Uncover the True Disease Load. Ivo Steinmetz, Gabriel E. Wagner, Estelle Kanyala, Mamadou Sawadogo, Hema Soumeya, Mekonnen Teferi, Emawayish Andargie, Biruk Yeshitela, Louise Yaba Atsé-Achi, Moussa Sanogo, Bassirou Bonfoh, Raphael Rakotozandrindrainy, Célestin Pongombo Shongo, Mick Shongoya Pongombo, Eric Kasamba Ilunga, Sabine Lichtenegger, Karoline Assig, Jürgen May, Eric Bertherat, Michael Owusu, Ellis Owusu-Dabo, Yaw Adu-Sarkodie. Trop Med Infect Dis. 2018 Jun; 3(2): 62. Published online 2018 Jun 10. doi: 10.3390/tropicalmed3020062


    1. Microbial pathogens associated with acute childhood diarrhoea in Kumasi, Ghana. Gilbert Kotei Ashie, Mohamed Mutocheluh, Michael Owusu, Theophilus Benjamine Kwofie, Samuel Akonor, Patrick Williams Narkwa, Samuel Blay Nguah, Joslin Dogbe. BMC Res Notes. 2017; 10: 264.



    1. Prevalence and risk factors of virological failure among children on antiretroviral therapy. Owusu Michael, Mensah Eric, Enimil Anthony, Mutocheluh Mohamed. BMJ Specialist Journals, 2017, Vol 2, Suppl 2.


    1. Health care workers indicate ill preparedness for Ebola Virus Disease outbreak in Ashanti Region of Ghana. Augustina Angelina Annan, Denis Dekugmen Yar, Michael Owusu, Eno Akua Biney, Paa Kobina Forson, Portia Boakye Okyere, Akosua Adumea Gyimah and Ellis Owusu-Dabo. BMC Public Health, 17:546:



    1. Current meningitis outbreak in Ghana: Historical perspectives and the importance of diagnostics. Alexander Kwarteng, John Amuasi, Augustina Annan, Samuel Ahuno, David Opare, Michael Nagel, Christof Vinnemeier, Jürgen May, Ellis Owusu-Dabo. Acta tropical, 2017, 169, 51-56


    1. Seroprevalence and occupational risk factors for Brucella infection among slaughterhouse workers and butchers in Kumasi, Ghana. Esimebia Adjovi Amegashie, Ellis Owusu-Dabo, Samson Pandam Salifu, Anthony Afum-Adjei Awuah, Sandra Baffour-Awuah, Nicholas Addofoh, Augustina Annan, Christian Henrik Winter. Journal of Epidemiological Research, 2017; 3(1)


    1. Effects of Changes in Haematological Parameters of Malaria Infected Children and Adult Patients Attending the St. Patrick’s Hospital, Offinso, Ghana. Ellis Kobina Paintsil, Augustina Angelina Sylverken, Matthew Glover Addo. International Journal of Current Research, 2019


    1. Graduate students’ interest in immunology as a discipline. Alexander Kwarteng, Michael Frimpong, Augustina Angelina Sylverken, Yarhands D Arthur, Samuel T Ahuno, Ellis Owusu-Dabo. Cogent Education, 2017; 4(1): 1398705


    1. Missed opportunities for the diagnosis of Brucella infection among slaughterhouse workers at the Kumasi Abattoir, Ghana. Esimebia Adjovi Amegashie, Augustina Angelina Annan, Anthony Afum-Adjei Awuah, Richard Larbi, Nicholas Addofoh, Patrick Kwame Feglo, Ellis Owusu-Dabo. J. Epidemilo. Res, 2017; 32: 58-64


    1. Pseudomonas oryzihabitans sepsis in a 1-year-old child with multiple skin rashes: a case report. Michael Owusu, Ellis Owusu-Dabo2*, Godfred Acheampong, Isaac Osei, John Amuasi, Nimako Sarpong, Augustina Annan, Hsin-Ying Chiang, Chih-Horng Kuo, Se Eun Park, Florian Marks and Yaw Adu-Sarkodie. Journal of Medical Case Report, 11:77:2017


    1. Performance of First Response® and CareStart™ Malaria Rapid Diagnostic Tests for the Detection of Plasmodium falciparum in a Tertiary Hospital in Ghana Bernice Ameyaw , Mohamed Mutocheluh, Michael Owusu, Alhassan Abiba Khalifah3 , Richard Vikpebah Duneeh3 and Patrick Williams Narkwa British Journal of Medicine & Medical Research 19(8): 1-7, 2017


    1. An ileal perforation associated with CTX-M and TEM extended spectrum β-lactamases- producing extended broad spectrum β-lactamase Escherichia coli: medical case report. Michael Owusu, Kojo Sarfo Marfo1, Isaac Osei,John Amuasi1, Nimako Sarpong, Augustina Annan, Ellis Owusu-Dabo ,Yaw Adu-Sarkodie. Clinical Reviews and Case Reports 2016, 3:1:140.


    1. Similar virus spectra and seasonality in paediatric patients with acute respiratory disease, Ghana and Germany. Annan, F Ebach, VM Corman, R Krumkamp, Y Adu-Sarkodie, AM Eis-Hübinger, T Kruppa, A Simon, J May, J Evans, M Panning, C Drosten, JF Drexler. Clinical Microbiology and Infection, 2016, 22(4), 340-346


    1. Insecticide resistance in malaria vectors in Kumasi, Ghana. Sandra Baffour-Awuah, Augustina A Annan, Oumou Maiga-Ascofare, Soma Diloma Dieudonné, Priscilla Adjei-Kusi, Ellis Owusu-Dabo, Kwasi Obiri-Danso. Parasites and Vectors, 2016, 9 (1), 1-8


    1. Bacterial etiology of sexually transmitted infections at a STI clinic in Ghana; use of multiplex real time PCR. Augustina A Sylverken, Ellis Owusu-Dabo, Denis D Yar, Samson P Salifu, Nana Yaa Awua-Boateng, John H Amuasi, Portia B Okyere, Thomas Agyarko-Poku. Ghana medical journal, 2016, 50 (3), 142-148


    1. Genotypic characterisation of human papillomavirus infections among persons living with HIV infection; a case–control study in Kumasi, Ghana. Denis Dekugmen Yar, Samson Pandam Salifu, Samuel Nkansah Darko, Augustina Angelina Annan, Akosua Adumea Gyimah, Kwame Ohene Buabeng, Ellis Owusu‐ Tropical Medicine & International Health, 2016, 21 (2), 275-282


    1. Dengue virus exposure among blood donors in Ghana. P. W. Narkwa, M. Mutocheluh, T. B. Kwofie, Owusu, A. Annan, I. Ali and J.K. Boamah. Journal of Medical and Biomedical Sciences (2016) 5(2): 30-35


    1. Sero-prevalence of rubella virus, cytomegalovirus and herpes simplex virus – 2 among pregnant women attending the ante-natal care unit at the Komfo Anokye Teaching Hospital. Theophilus Benjamin Kwofie, Frederick Ayensu, Mohamed Mutocheluh, Patrick Narkwa, Samuel Blay Nguah, Michael Owusu. Journal of Public Health in Developing Countries, vol. 1, No. 2, pp 56-63.


    1. Assessment of prison life of persons with disability in Ghana. Joslin Dogbe, Ellis Owusu-Dabo, Anthony Edusei, Gyikua Plange-Rhule, Nicholas Addofoh, Sandra Baffour-Awuah, Osei Sarfo-Kantanka, Charles Hammond, Michael Owusu. 2016/12. BMC international health and human rights



    1. Knowledge and practice of malaria prevention among caregivers of children with malaria admitted to a teaching hospital in Ghana. Emmanuel Ameyaw, Joslin Dogbe, Michael Owusu. 2015/8/1 Asian Pacific Journal of Tropical Disease


    1. Pain Description and Presentation in Children Admitted to a Teaching Hospital in Ghana. CK Hammond, J Dogbe, V Paintsil, L Tutu, M Owusu. 2015 Journal J Cancer Prev Curr Res



    1. A novel rhabdovirus isolated from the straw-colored fruit bat Eidolon helvum, with signs of antibodies in swine and humans. Tabea Binger, Augustina Annan, Jan Felix Drexler, Marcel Alexander Müller, René Kallies, Ernest Adankwah, Robert Wollny, Anne Kopp, Hanna Heidemann, Dickson Dei, Festus Courage Agya-Yao, Sandra Junglen, Torsten Feldt, Andreas Kurth, Samuel Oppong, Yaw Adu-Sarkodie, Christian Drosten. Journal of Virology, 2015, 89 (8), 4588-4597


    1. Evidence for an ancestral association of human coronavirus 229E with bats. Corman VM, Baldwin HJ, Fumie Tateno A, Melim Zerbinati R, Annan A, Owusu M, Nkrumah EE, Maganga GD, Oppong S, Adu-Sarkodie Y, Vallo P, da Silva Filho LV, Leroy EM, Thiel V, van der Hoek L, Poon LL, Tschapka M, Drosten C, Drexler JF. J Virol. 2015 Sep 16, JVI.01755-15.



    1. Pattern and Predictors of Immunologic Recovery in HIV infected patients: Observations from Two Health Facilities in Ghana. Theophilus B Kwofie, Michael Owusu, Mohamed Mutocheluh, Samuel Blay Nguah, Joseph Obeng-Baah, Charlotte Hanson, Albert Dompreh. BMC Res Notes 2015 Sep 4; 8(1):413.


    1. MERS-CoV-related viruses in bats in Ghana and Europe. Annan A A, Baldwin H J, Corman V M, Klose SM, Owusu M, Nkrumah E E, Badu E K, Anti P, Agbenyega O, Meyer B. Epidemiology and ecology of virus and host: bats and coronaviruses in Ghana, West Africa, 2015, Page 17.


    1. Widespread coronavirus infection in Ghanaian bats: seasonal, demographic and ecological factors influence infection risk. Baldwin H, Corman V, Nkrumah E, Badu E K, Anti P, Annan A A, Owusu M, Agbenyega O, Oppong S K, Klose S M. Epidemiology and ecology of virus and host: bats and coronaviruses in Ghana, West Africa, 2015, Page 30.


    1. Highly divergent hepaciviruses from African cattle. Victor Max Corman, Adam Grundhoff, Christine Baechlein, Nicole Fischer, Anatoly Gmyl, Robert Wollny, Dickson Dei, Daniel Ritz, Tabea Binger, Ernest Adankwah, Kwadwo Sarfo Marfo, Lawrence Annison, Augustina Annan, Yaw Adu-Sarkodie, Samuel Oppong, Paul Becher, Christian Drosten, Jan Felix Drexler. Journal of Virology, 2015, Vol 89, Issue 11, pages 5876-5882


    1. Serological evidence of influenza A viruses in frugivorous bats from Africa. Gudrun Stephanie Freidl, Tabea Binger, Marcel Alexander Müller, Erwin de Bruin, Janko van Beek, Victor Max Corman, Andrea Rasche, Jan Felix Drexler, Augustina Sylverken, Samuel K Oppong, Yaw Adu-Sarkodie, Marco Tschapka, Veronika M Cottontail, Christian Drosten, Marion Koopmans. PLoS one, 2015, Vol 10, Issue 5, e0127035


    1. No evidence of Gouleako and Herbert virus infections in pigs, Cote d’Ivoire and Ghana. Sandra Junglen, Marco Marklewitz, Florian Zirkel, Robert Wollny, Benjamin Meyer, Hanna Heidemann, Sonja Metzger, Augustina Annan, Dickson Dei, Fabian H Leendertz, Samuel Oppong, Christian Drosten. Emerging Infectious Diseases, 2015; 21 (12): 2190


    1. Palp ratio as a field identification tool for two members of the Anopheles gambiae complex in Ghana (A. melas and A. gambiae). Augustina Angelina Annan, Thomas Florian Kruppa, Ohene Adjei, Rolf Garms. Parasites & Vectors, 2015; 8(1): 1-4


    1. Human–Bat Interactions in Rural West Africa. Priscilla Anti, Michael Owusu, Olivia Agbenyega, Augustina Annan, Ebenezer Kofi Badu,Evans Ewald Nkrumah, Marco Tschapka,Samuel Oppong, Yaw Adu-Sarkodie, Christian Drosten. Emerging Infectious Diseases.Vol. 21, No. 8, August 2015.



    1. High prevalence of common respiratory viruses and no evidence of Middle East Respiratory Syndrome Coronavirus in Hajj pilgrims returning to Ghana, 2013. Augustina Annan, Michael Owusu Kwadwo Sarfo Marfo, Richard Larbi, Francisca Naana Sarpong, Yaw Adu-Sarkodie, Joseph Amankwa, Samuel Fiafemetsi, Christian Drosten, Ellis Owusu-Dabo, Isabella Eckerle. Tropical Medicine & International Health 02/2015; 20(6).


    1. Lysinibacillus sphaericus biolarvicide, an efficacious tool in the control of Anopheles gambiae in Kumasi, Ghana. Sandra Baffour-Awuah, Ellis Owusu-Dabo, Thomas Kruppa, Augustina Annan, Rita Nartey, Joslin Dogbe, Samson Pandam Salifu, Norbert Becker, Samuel Kingsley Oppong, Kwasi Obiri-Danso. 2014


    1. Health-Seeking behaviour of TB patients and related factors in the Central Region of Ghana. Augustina Angelina Annan. International Journal of Infectious Diseases, 2014; 21: 309


    1. Insecticide resistance in malaria vector mosquitoes at 5 selected districts in Ghana, West Africa. Augustina A Annan, Ellis Owusu-Dabo, Sandra Baffour-Awuah, Rita Nartey, Nimako Sarpong, Abonuusum G Ayimbire, Samson Pandam Salifu, Amoyaw Frank, Segbaya Sylvester, Buabeng K Ohene. East African Journal of Public Health, 2014


    1. Human coronaviruses associated with upper respiratory tract infections in three rural areas of Ghana. Owusu M, Annan A, Corman VM, Larbi R, Anti P, Drexler JF, Agbenyega O, Adu-Sarkodie Y, Drosten C. PLoS One. 2014 Jul 31;9(7). Emerging Infectious Disease. 2013 Mar;19(3):456-9.



    1. Evidence for novel hepaciviruses in rodents. Jan Felix Drexler, Victor Max Corman, Marcel Alexander Müller, Alexander N Lukashev, Anatoly Gmyl, Bruno Coutard, Alexander Adam, Daniel Ritz, Lonneke M Leijten, Debby Van Riel, Rene Kallies, Stefan M Klose, Florian Gloza-Rausch, Tabea Binger, Augustina Annan, Yaw Adu-Sarkodie, Samuel Oppong, Mathieu Bourgarel, Daniel Rupp, Bernd Hoffmann, Mathias Schlegel, Beate M Kümmerer, Detlev H Krüger, Jonas Schmidt-Chanasit, Alvaro Aguilar Setién, Veronika M Cottontail, Thiravat Hemachudha, Supaporn Wacharapluesadee, Klaus Osterrieder, Ralf Bartenschlager, Sonja Matthee, Martin Beer, Thijs Kuiken, Chantal Reusken, Eric M Leroy, Rainer G Ulrich, Christian Drosten. PLos pathogens, 2013, Vol 9, Issue 6, e1003438


    1. Bats carry pathogenic hepadnaviruses antigenically related to hepatitis B virus and capable of infecting human hepatocytes. Jan Felix Drexler, Andreas Geipel, Alexander König, Victor M Corman, Debby van Riel, Lonneke M Leijten, Corinna M Bremer, Andrea Rasche, Veronika M Cottontail, Gael D Maganga, Mathias Schlegel, Marcel A Müller, Alexander Adam, Stefan M Klose, Aroldo José Borges Carneiro, Andreas Stöcker, Carlos Roberto Franke, Florian Gloza-Rausch, Joachim Geyer, Augustina Annan, Yaw Adu-Sarkodie, Samuel Oppong, Tabea Binger, Peter Vallo, Marco Tschapka, Rainer G Ulrich, Wolfram H Gerlich, Eric Leroy, Thijs Kuiken, Dieter Glebe, Christian Drosten. Proceedings of the National Academy of Sciences 2013, Vol 110, Issue 40, pages 16151-16156


    1. Risk factors associated with hepatitis B exposure and the reliability of five rapid kits commonly used for screening blood donors in Ghana. M Mutocheluh, M Owusu, TB Kwofie, T Akadigo, E Appau, PW Narkwa. BMC research notes 7 (1), 873



    1. Use of Bacillus thuringiensis var israelensis as a viable option in an Integrated Malaria Vector Control Programme in the Kumasi Metropolis, Ghana. Rita Nartey, Ellis Owusu-Dabo, Thomas Kruppa, Sandra Baffour-Awuah, Augustina Annan, Samuel Oppong, Norbert Becker, Kwasi Obiri-Danso. Parasites & vectors, 2013, Vol 6, Issue 1, Pages 1 – 10


    1. Human betacoronavirus 2c EMC/2012-related viruses in bats, Ghana and Europe. Annan A, Baldwin HJ, Corman VM, Klose SM, Owusu M, Nkrumah EE, Badu EK, Anti P, Agbenyega O, Meyer B, Oppong S, Sarkodie YA, Kalko EK, Lina PH, Godlevska EV, Reusken C, Seebens A, Gloza-Rausch F, Vallo P, Tschapka M, Drosten C, Drexler JF.Emerg Infect Dis. 2013 Mar;19(3):456-9



    1. Health-seeking behaviour of tuberculosis patients and related factors in the central region of Ghana. AA Annan, A Singh, JA Dogbe, D Asante, Ellis Owusu-Dabo. Journal of Science and Technology, 2013; 33(3): 27-38


    1. Aetiological agents of cerebrospinal meningitis: a retrospective study from a teaching hospital in Ghana. Owusu M, Nguah SB, Boaitey YA, Badu-Boateng E, Abubakr AR, Lartey RA, Adu-Sarkodie Y. Ann Clin Microbiol Antimicrob. 2012 Oct 4; 11:28


    1. Respiratory viruses in children hospitalized for acute lower respiratory tract infection in Ghana. Kwofie TB, Anane YA, Nkrumah B, Annan A, Nguah SB, Owusu M. Virol J. 2012 Apr 10; 9:78.


    1. Human parvovirus 4 in nasal and fecal specimens from children, Ghana. Jan Felix Drexler, Ulrike Reber, Doreen Muth, Petra Herzog, Augustina Annan, Fabian Ebach, Nimarko Sarpong, Samuel Acquah, Julia Adlkofer, Yaw Adu-Sarkodie, Marcus Panning, Egbert Tannich, Jürgen May, Christian Drosten, Anna Maria Eis-Hübinger. Emerging infectious diseases, 2012, 18 (10), 1650


    1. The effect of alpha (+)-Thalassaemia on P. falciparum Malaria parasitaemia in children attending Komfo Anokye Teaching Hospital. K Franklin, C Opoku-Okrah, K Obiri-Danso, WKBA Owiredu, Augustina Angelina Sylverken. 2011



    1. Hepatitis B and C viral infections among blood donors. A retrospective study from a rural community of Ghana. B Nkrumah, M Owusu, P Averu. BMC research notes 4 (1), 529


    1. Distant relatives of severe acute respiratory syndrome coronavirus and close relatives of human coronavirus 229E in bats, Ghana. Susanne Pfefferle, Samuel Oppong, Jan Felix Drexler, Florian Gloza-Rausch, Anne Ipsen, Antje Seebens, Marcel A Müller, Augustina Annan, Peter Vallo, Yaw Adu-Sarkodie, Thomas F Kruppa, Christian Drosten. Emerging infectious diseases, 2009, Vol 15, Issue 9, Page 1377


    1. A novel diagnostic target in the hepatitis C virus genome. Jan Felix Drexler, Bernd Kupfer, Nadine Petersen, Rejane Maria Tommasini Grotto, Silvia Maria Corvino Rodrigues, Klaus Grywna, Marcus Panning, Augustina Annan, Giovanni Faria Silva, Jill Douglas, Evelyn S C Koay, Heidi Smuts, Eduardo M Netto, Peter Simmonds, Maria Inês de Moura Campos Pardini, W Kurt Roth, Christian Drosten. PLoS medicine, 2009, Vol 6, Issue 2, e1000031


    1. Bacterial Urinary Tract Infections among Males with Lower Urinary Tract Obstruction at Komfo Anokye Teaching Hospital, Kumasi, Ghana. Christian Kofi Gyasi-Sarpong, Edwin Mwintiereh Ta-ang Yenli, Ali Idriss, Addae Appiah Arhin, Ken Aboah, Roland Azorliade, Yaw Agyekum Boaitey, Augustina Angelina Annan. 2012


    1. Henipavirus RNA in African bats. Jan Felix Drexler, Victor Max Corman, Florian Gloza-Rausch, Antje Seebens, Augustina Annan, Anne Ipsen, Thomas Kruppa, Marcel A Müller, Elisabeth KV Kalko, Yaw Adu-Sarkodie, Samuel Oppong, Christian Drosten. PloS one, 2009, Vol 4, Issue 7, e6367


    1. No evidence of chikungunya virus and antibodies shortly before the outbreak on Sri Lanka. Marcus Panning, Dominic Wichmann, Klaus Grywna, Augustina Annan, Sriyal Wijesinghe, SAM Kularatne, Christian Drosten. Medical Microbiology and Immunology, 2009, Vol 198, pages 103-106


    1. Detection and prevalence patterns of group I coronaviruses in bats, northern Germany. Florian Gloza-Rausch, Anne Ipsen, Antje Seebens, Matthias Göttsche, Marcus Panning, Jan Felix Drexler, Nadine Petersen, Augustina Annan, Klaus Grywna, Marcel Müller, Susanne Pfefferle, Christian Drosten. Emerging infectious diseases, 2008, Vol 14, Issue 4, page 626
  1. Augustina Angelina Sylverken – Group Leader
  2. Michael Owusu – Co-Principal Investigator
  3. Richmond Yeboah – Doctoral Student
  4. Miss Sherihane Aryeetey – Doctoral Student
  5. Richmond Gorman -Master Student
  6. Henry Kyeremateng Acheampong – Master Student
  7. Jesse Addo Asamoah – Master Student
  8. Miss Henrietta Dede Tetteh – Master Student
  9. Miss Manuella Hayford -Master Student
  10. Mr. Michael Adu-Brew – Research Assistant

Group Leader

Dr Augustina Angelina Sylverken
Phone: +233 244 214625

Co- Principal Investigator:

Dr Micheal Owusu
Phone: +233 24 340 9558


Prof. Christian Drosten


Dr. Philip El-Duah

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