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Introduction to Clinical Research and Development

 Kumasi Centre for Collaborative Research (KCCR),

Introduction to Clinical Research and Development

Course date: May 15- 26, 2017

Venue: KCCR Seminar Room


Course Overview

This course is an intensive, two-week, full-time (09.00 hours to 17.00 hours, Monday-Friday) course in Clinical Research and Development for health-related workers. It covers the basic concepts of clinical research and provides an introductory overview aimed at everyone involved in clinical research and focuses on the main areas of why and how clinical research is carried out and the importance of ethics in research.

It shall combine practical case studies series of lectures and seminars designed to equip participants with the practical and contextual knowledge of implementing clinical trials.

Faculty on the course, most of whom have extensive years of research in clinical research will come from Ghana and South Africa. The course will provide the setting for hands-on case studies and interaction with faculty as well as cutting edge didactic teaching.

Aims of the Course

The course aims to teach participants in the health profession the skills required to understand and undertake clinical studies. It is intended to introduce participants to the design, conduct and management of clinical studies with special emphasis on Research ethics, pharmacovigilance and Good clinical practice among others

Course outline

Much of the course time will be devoted to lectures and seminars, during which a multi-disciplinary team of experts will cover thematic modules in great detail. Lectures will cover the following areas:

  • Research ethics
  • Study design
  • Study protocol
  • ICH-GCP
  • GCLP
  • Informed consent
  • Collecting and Reporting Adverse Events
  • Pharmacovigilance
  • Data management in clinical research
  • Children and Clinical Research
  • Trial design and management
  • Conducting GCP Inspections/Audits at the Clinical Investigator Site
  • Conducting trials in resource limited setting (Africa)
  • Community engagement in research implementation
  • Intellectual property management.

Time will be set aside after each lecture for discussions and case studies that will allow participants to put to direct use what they have studied. Additionally, lectures will be followed by interactive sessions with faculty to allow participants the opportunity to follow up on lectures that time could not permit complete exhaustion of content. It would also allow faculty to get to know course participants and share personal experiences in relevant modules that could not have been discussed during the scheduled period. Time will also be set aside during the course period for networking

Course fee/Scholarships (does not include air fares)

This course is being organized with sponsorship from WHO-TDR. Therefore, participants shall be selected on the basis of full funding under the auspices of the funder. This covers course tuition, course materials and feeding but does NOT include accommodation.

 

Who should apply for the course?

The course is open to early career research scientists and staff in the field of clinical and biomedical research. This includes postgraduate students, laboratory technologists and technicians, Post-docs, Medical Doctors, Nurses, District health directors, Health program managers and lecturers.

Applicants must have a good standard of written and spoken English.

Accommodation

This will be a daily course held from 9.00-18.00 hours. Participants will be responsible for their accommodation arrangements.

How to apply

Please download the application form here, and include the following:

  • The completed application form,
  • One-page personal motivation statement of purpose (500 words),
  • A one-page letter explaining how the course will contribute to your career development (500 words)
  • Two (2) letters of recommendation

Send to:

 The Course Facilitator

(e-mail: afumadjeiawuah@kccr.de; Tel. no. +233 242 107 721)

 Deadline for application is Sunday 30th April 2017

 

 

 

 

CERTIFICATE COURSE IN TROPICAL MEDICINE

Certificate Course in Tropical Medicine, organized by the Kumasi Centre for Collaborative Research (KCCR), College of Health Sciences, KNUST, Kumasi, and the Bernhard Nocht Institute for Tropical Medicine (BNITM), Hamburg, Germany.

Course date: 21st Nov – 2nd Dec, 2016
Venue: KNUST, Kumasi, Ghana

Overview

The Certificate Course in Tropical Medicine (CCTM) is an intensive,
two-week, full-time course in Tropical Medicine for health-related workers.

It combines practical work, a series of lectures and seminars designed to equip potential attendees with the practical and factual knowledge of Tropical Medicine.

Faculty on the course, most of whom have lived and worked in the tropics will come from Ghana and Germany. The KCCR laboratories will provide the setting for hands-on laboratory work as well as cutting edge didactic teaching.

Aims of the Course

The course aims to teach people in the health profession the skills required to understand, diagnose, treat and prevent diseases that are especially prevalent in tropical and developing countries where resources may be limited. The course has a strong epidemiological base but the scientific basis of tropical infectious diseases will also be given priority.

Course outline

Much of the course will be devoted to lectures and seminars, during which a multi-disciplinary team of experts will cover a particular disease or group of diseases in depth. Lectures will cover the causative organisms, epidemiology, pathogenesis, clinical features, diagnosis, management and prevention of these diseases. Time will be set aside after each lecture for discussion.

Lectures will be followed by practical sessions during which the laboratory diagnosis of the major diseases will be taught. The course is intensive, without much free time during the two weeks and continues until 17.00 hours. However, weekends are free and a field trip has been planned for this year’s course.

Accreditation

The Academic Board of the Kwame Nkrumah University of Science and Technology has approved the curriculum of the CCTM.

Course fee/Scholarships (does not include air fares)

European countries – 1,500 Euros (Course fee, lodging and feeding)

African countries – 800 Euros (Course, lodging and feeding)

Ghanaian residents: 2000 New Ghana cedis (Course and feeding)

Who should apply for the course?

The CCTM course is open to workers in the medical field. This includes students (Post-grads), Epidemiologists, Research Scientists, Post-Docs, Medical Doctors, Clinical students, District health directors, etc.

Applicants must have a good standard of written and spoken English.

Accommodation

The CCTM will NOT provide residential accommodation, but a wide range of student accommodation is available on Campus. A number of University Halls of Residence provide accommodation. There are private hostels run by other organizations as well as many privately-rented lodgings, flats or houses.

How to apply

Please download the application form online, and send the completed application form, one-page motivation statement of purpose, a CV and two (2) letters of reference to:

The Course Facilitator
(e-mail: info@kccr.de; Tel. no. +233 32 2060351)

Deadline for application is Friday 11th November 2016

DELGEME CALL FOR MSC, PHD AND POST-DOCTORAL FELLOWSHIPS

DELGEME CALL FOR MSC, PHD AND POST-DOCTORAL FELLOWSHIPS

The Developing Excellence in Leadership and Genetics Training for Malaria Elimination in sub-Saharan Africa (DELGEME) programme is launching new calls for MSc, PhD, Post Docs to start in 2016

Background

The Developing Excellence in Leadership and Genetics Training for Malaria Elimination in sub-Saharan Africa (DELGEME) is a new training programme sponsored by the Wellcome Trust Developing Excellence in Leadership, Training and Science Africa (DELTAS Africa) initiative in partnership with the Department of International Development (DFID) and the Alliance for Accelerating Excellence in Science in Africa (AESA). The partner institutions are the University of Science Techniques and Technologies of Bamako Mali (USTTB), Medical Research Council (MRC) Unit in The Gambia, The United States Army Medical Research Directorate (USAMRD-K)/KEMRI Kenya, The Noguchi Memorial Institute for Medical Research (NMIMR)-Navrongo Health Research Centre, Ghana, The National Institute of Medical Research (NIMR) Tanzania, Université des Sciences de la Santé of Libreville, Gabon, Benhard-Nocht Institute for Tropical Medicine (BNITM) Germany/Kumasi Centre for Collaborative Research (KCCR) Ghana, and the University of Oxford/Wellcome Trust Sanger Institute UK.
It is led by USTTB with MRC and USAMRD-K/KEMRI as the training hubs. In collaboration with MalariaGEN (www.malariagen.net) and the Plasmodium Diversity Network Africa (PDNA, http://www.cggh.org/collaborations/plasmodium-diversity-network-africa), DELGEME aims to enrich the pool of African Scientists working in African institutions with relevant expertise to leverage big genetics and genomics data in the drive for malaria elimination in sub-Saharan Africa.
Over the next five years, DELGEME will be providing short-term and degree training (MSc, PhD, Post-doctoral) to at least 90 young African scientists. Fellowships will be hosted at an African institution with a curriculum in genetics, genomics, bioinformatics, biostatistics, data science and ethical issues in genetics/genomics. DELGEME fellows are expected to develop a research proposal that explore critical gaps in malaria genetics and molecular epidemiology to aid the malaria elimination agenda. Dedicated computational facilities will be available for fellows at the USTTB, the MRC, and USAMRD/KEMRI.

Objectives

To develop advanced technical and analytical skills of African scientists in relevant areas of bioinformatics, next generation sequence analysis, population genetics, epidemiology, statistical and cellular/molecular biology of parasites, hosts and vectors in collaboration with local and International partners for malaria control and elimination in sub-Saharan Africa.
The specific aims of this call are to invite applicants for MSc, PhD and Post-Doctoral training in the above fields.

Evaluation criteria

  1. The candidate’s qualifications and motivations;
  2. The research quality of the project (for PhDs and Post-docs);
  3. The relevance of the proposed project in relation to the objectives of the call for proposals (for PhDs and Post-Docs);
  4. The academic basis of the PhD or Post-doc project at the relevant University or partner Institution.

Who can apply?

Only candidates who are nationals of PDNA memberi countries are eligible to respond to this call. It is a prerequisite that applications and projects are prepared in collaboration with at least one PDNA member institutionii. Prospective candidate must enroll or be currently enrolled for MSc or PhD in an appropriate Graduate School within Africa. For PhDs and Post-Doctoral fellows, it must be clearly demonstrated in the application that the proposed project is affiliated with an active research environment at a University/Research Institution. Candidates with an undergraduate training in computational, mathematics and physical sciences are also encouraged to apply.

Financial framework

The grant for each MSc fellowship will be up to £26,000 for two years or £13,000 for candidates who have already completed 1 year in a related curriculum towards a MSc. PhD fellowship will be up to £63,000 for 3 years and Post-doctoral fellowship will be up to £120,000 for 3 years. This amount includes student’s stipend, research cost, and other training/research related costs. The final amount awarded will be determined at the time of award notification.

Application procedure:
Step 1
Candidates must provide the following supporting documentation as part of their application
1. A cover page including Personal informations:
a. Full names as they appear on applicant’s ID/passport;
b. Full contact details, including residential and postal address; email and telephone number(s); and
c. Name of institution at which the applicant wishes to undertake his/her training/degree (Master, PhD studies, Postdoctoral) study.
2. Letter of support from the prospective host PDNA Supervisor
3. A motivation letter (not longer than one A4 page – 500 words)
4. A research proposal outlining the problem statement, methodology, feasibility of the study and the contribution that it will make to the body of knowledge in the particular field of study (PhDs and Post-Doctoral Fellows only) (not longer than five A4 pages).
5. Two letters of recommendation from academic referees.
6. A certified copy of full academic transcript/s and certificates?
7. A copy of ID/passport
8. The most current CV (maximum 2 pages).

Step 2
The application must be submitted electronically to delgemecalls@delgeme.org and consists of the full application and the appendices. The appendices template and guidelines can be downloaded from the website www.delgeme.org

The deadline for applications is:
Sunday 30 September 2016 at 17:00GMT for MSc fellowships and
Tuesday 30 October 2016 at 17:00 GMT for PhDs and Post-Doctoral Fellows.
Applicants will receive an email to confirm receipt shortly after the application is received.

Contacts
For further information, please contact the DELGEME office:
Prof. Djibril Sangare
Programme Manager DELGEME
University of Science, Techniques and Technology of Bamako (USTTB) P.O. Box: 1805 Point G, Bamako; Mali (West Africa)
Phone: +223 75160745/ +223 99963095

iPlasmodium Diversity Network Africa, PDNA (http://www.cggh.org/collaborations/plasmodium-diversity-network-africa; (South Africa, Angola, Cameroon, Côte d’Ivoire, Cape Vert, Ethiopia, Gabon, Ghana, The Gambia, Kenya, Madagascar, Mali, Mozambique, RD Congo and Tanzania)
ii Abdoulaye Djimde (adjimde@icermali.org)/Malaria Research and Training Center – University of Science, Techniques and Technologies of Bamako, Mali; Milijaona Randrianarivelojosia (milijaon@pasteur.mg)/Institut Pasteur de Madagascar; Antoinette Tshefu-Kitoto (antotshe@yahoo.com) & Dieudonne Mumba (mumbadieudonne@yahoo.fr)/ University of Kinshasa; Paulina Tindana (ptindana@gmail.com)&Lucas Amenga-Etego (lucasmenga@gmail.com)/ Navrongo Health Research Center (NHRC); Lemu Golassa (lgolassa@gmail.com)/ Addis Ababa University, Ethiopia; Tobias Apinjoh (apinjoh.tobiasa@ubuea.cm)/ University of Buea; Yavo William (yavowilliam@yahoo.fr)/ University FHB of Abidjan – National Institute of Public Health, Côte d’Ivoire; Alfredo Mayor (alfredo.mayor@isglobal.org)/ Centro de Investigaçao em Saúde de Manhiça (CISM) and Barcelona Institue for Global Health (ISGlobal); Jaishree Raman (JaishreeR@nicd.ac.za) / National Institute for Communicable Diseases (NICD); Joana Alves/ Instituto Nacional de SaúdePública, Ministério da Saúde de Cabo Verde ; Maria Do Rosario Bragança Sambo (rosariosambo@hotmail.com) / Faculty of Medicine of KatyavalaBwila University; Alfred Amambua-Ngwa (angwa@mrc.gm)/Medical Research Council Unit The Gambia; Anita Ghansah (aghansah2013@gmail.com)/Noguchi Memorial Institute for Medical Research; Oumou Maiga-Ascofare (maiga@bni-hamburg.de) /Benhard-Nocht Institute for Tropical Medicine (BNITM) – Kumasi Centre for Collaborative Research (KCCR); Deusdedith Ishengoma (deusishe@yahoo.com)/National Institute for Medical Research; Marielle Bouyou-Akotet (mariellebouyou@yahoo.fr)/Université des Sciences de la Santé, Libreville; Maj Matthew Brown (Matthew.Brown@usamru-k.org), Ben Andagalu (ben.andagalu@usamru-k.org) & Edwin Kamau (edwin.kamau.mil@mail.mil)/ United states Army Research Directorate-Kenya

Publications 2016

1.     Frank C, Krumkamp R, Sarpong N, Sothmann P, Fobil JN, Foli G, Jaeger A, Ehlkes L, Owusu-Dabo E, Adu-Sarkodie Y, Marks F, Schumann RR, May J, Kreuels B. Spatial heterogeneity of malaria in Ghana: a cross-sectional study on the association between urbanicity and the acquisition of immunity. Malar J. 2016;15(1):84. doi: 10.1186/s12936-016-1138-4.

2. Sarkodie F, Owusu-Dabo E, Owusu-Ofori S, Bates I, Bygbjerg IC, Ansah JK, Ullum H. Syphilis screening practices in blood transfusion facilities in Ghana. International Journal of Infectious Diseases (2016); 43: 90-4. Doi:10.1016/j.ijid.2015.12.020

3. Sarkodie F, Ullum H, Owusu-Dabo E, Owusu-Ofori S, Owusu-Ofori A, Hassal O. A novel strategy for screening blood donors for syphilis at Komfo Anokye Teaching Hospital, Ghana. Transfusion Medicine. 2016. Doi: 10.1111/tme.12279.

4. Danquah DA, Buabeng KO, Asante KP, Mahama E, Bart-Plange C, Owusu-Dabo E. Malaria case detection using rapid diagnostic test at the community level in Ghana: consumer perception and practitioners’ experiences. Malar J. 2016; 15 (1): 34.doi: 10.1186/s12936-016-1086-z

5.     Addai-Mensah O, Seidel M, Amidu N, Maskus DJ, Kapelski S, Breuer G, Franken C, Owusu-Dabo E, Frempong M, Rakotozandrindrainy R, Schinkel H, Reimann A, Klockenbring T, Barth Stefan, Fishcer Rainer, Fendel R. Acquired immune response to three malaria vaccine candidates and their relationship to invasion inhibition in two populations naturally exposed to malaria. Malar J. 2016, 15 (1): 65. Doi:10.1186/s12936-016-1112-1
6. Yar, D.D., Salifu, S.P., Darko, S.N., Annan, A.A., Gyimah, A.A., Buabeng, K.O. and Owusu-Dabo, E. (2016). Genotypic characterization of human papillomavirus infections among persons living with HIV infection; a case-control study in Kumasi, Ghana.. Trop Med Int Health, 21(2):275-82.

7. Vinnemeier, C.D., Klupp, E.M., Krumkamp, R., Rolling, T., Fischer, N., Owusu-Dabo, E., Addo, M.M., Adu-Sarkodie, Y., Käsmaier, J., Aepfelbacher, M., Cramer, J.P., May, J. and Tannich, E. (2016). Tropheryma whipplei in children with diarrhoea in rural Ghana. Clin Microbiol Infect, 22(1):65.e1-3

8. Mulder, N.J., Adebiyi, E., Alami, R., Benkahla, A., Brandful, J., Doumbia, S., Everett, D., Fadlelmola, F.M., Gaboun, F., Gaseitsiwe, S., Ghazal, H., Hazelhurst, S., Ibrahimi, A., Hide, W., Jaufeerally Fakim, Y., Jongeneel, V., Joubert, F., Kassim, S., Kayondo, J., Kumuthini, J., Lyantagaye, S., Makani, J., Alzohairy, A.M., Masiga, D., Moussa, A., Nash, O., Ouwe Missi Oukem-Boyer, O., Owusu-Dabo. E., Panji, S., Patterton, H., Radouani, F., Sadki, K., Seghrouchni, F., Tastan Bishop, Ö., Tiffin, N. and Ulenga, N.; H3ABioNet Consortium. (2016). H3ABioNet, a sustainable Pan-African Bioinformatics Network for Human Heredity and Health in Africa. Genome Res., 26(2): 271-7

9. Stockdale, A.J., Phillips, R.O. and Geretti, A.M.; HEPIK Study Group (2016). The gamma-glutamyl transpeptidase to platelet ratio (GPR) shows poor correlation with transient elastography measurements of liver fibrosis in HIV-positive patients with chronic hepatitis B in West Africa. Response to: ‘The gamma-glutamyl transpeptidase to platelet ratio (GPR) predicts significant liver fibrosis and cirrhosis in patients with chronic HBV infection in West Africa’ by Lemoine et al. Gut, pii: gutjnl-2015-311133. doi: 10.1136/gutjnl-2015-311133.

Publications 2015

1. Darko, S.N., Yar, D.D., Owusu-Dabo, E,. Afum-Adjei Awuah, A., Dapaah, W., Addofoh, N., Salifu, S.P., Awua-Boateng, NY. and Adomako-Boateng, F. (2015). Variations in levels of IL-6 and TNF-α in type 2 diabetes mellitus between rural and urban Ashanti Region of Ghana. BMC Endocrine Disorders, 15:50.doi:10.1186/s12902-015-0047-9.

2. Sondo, P., Derra, K., Diallo-Nakanabo, S., Tarnagda, Z., Zampa, O., Kazienga, A., Valea, I., Sorgho, H., Owusu-Dabo, E., Ouedraogo, J.B., Guiguemde, T.R. and Tinto, H. (2015). Effectiveness and safety of artemether-lumefantrine versus artesunate-amodiaquine for unsupervised treatment of uncomplicated falciparum malaria in patients of all age groups in Nanoro, Burkina Faso: a randomized open label trial. Malar J., 14(1):325. doi: 10.1186/s12936-015-0843-8.

3. Nakua, E.K., Otupiri, E., Dzomeku, V.M., Owusu-Dabo, E., Agyei-Baffour, P., Yawson, A.E., Folson, G. and Hewlett, S. (2015). Gender disparities of chronic musculoskeletal disorder burden in the elderly Ghanaian population: study on global ageing and adult health (SAGE WAVE 1). BMC Musculoskelet Disord, 16:204. doi: 10.1186/s12891-015-0666-3

4. Vinnemeier, C.D., Brust, P., Owusu-Dabo, E., Sarpong, N., Sarfo, E.Y., Bio, Y., Rolling, T., Dekker, D., Adu-Sarkodie, Y., Eberhardt, K.A,. May, J. and Cramer JP. (2015). Group B Streptococci Serotype Distribution in Pregnant Women in Ghana: Assessment of Potential Coverage Through Future Vaccines. Trop Med Int Health. doi: 10.1111/tmi.12589

5. Meyer, C.G., Intemann, C.D., Förster, B., Owusu-Dabo, E., Franke, A., Horstmann, R.D. and Thye, T. (2015). No significant impact of IFN-γ pathway gene variants on tuberculosis susceptibility in a West African population. Eur J Hum Genet., doi: 10.1038/ejhg.2015.172.

6. Sarpong, N., Owusu-Dabo, E., Kreuels, B., Fobil, J.N., Segbaya, S., Amoyaw, F., Hahn, A., Kruppa. T. and May, J. (2015). Prevalence of malaria parasitaemia in school children from two districts of Ghana earmarked for indoor residual spraying: a cross-sectional study. Malar J., 14:260. doi: 10.1186/s12936-015-0772-6

7. Badu, K., Gyan, B., Appawu, M., Mensah, D., Dodoo, D., Yan, G., Drakeley, C., Zhou, G., Owusu-Dabo, E. and Koram, K.A. (2015). Serological evidence of vector and parasite exposure in Southern Ghana: the dynamics of malaria transmission intensity. Parasit Vectors, 8:251. doi: 10.1186/s13071-015-0861-y.

8. Annan, A., Owusu, M., Marfo, K.S., Larbi, R., Sarpong, F.N., Adu-Sarkodie, Y., Amankwa, J., Fiafemetsi, S., Drosten, C., Owusu-Dabo, E. and Eckerle, I. (2015). High prevalence of common respiratory viruses and no evidence of Middle East respiratory syndrome coronavirus in Hajj pilgrims returning to Ghana, 2013. Trop Med Int Health, 20(6): 807-812.

9. Agyemang, C., Beune, E., Meeks, K., Owusu-Dabo, E., Agyei-Baffour, P., Aikins, Ad., Dodoo, F., Smeeth, L., Addo, J., Mockenhaupt, F.P., Amoah, S.K., Schulze, M.B., Danquah, I., Spranger, J., Nicolaou, M., Klipstein-Grobusch, K., Burr, T., Henneman, P., Mannens, M.M., van Straalen, J.P., Bahendeka, S., Zwinderman, A.H., Kunst, A.E. and Stronks, K. (2015). Rationale and cross-sectional study design of the Research on Obesity and type 2 Diabetes among African Migrants: the RODAM study. BMJ Open, 4(3):e004877. doi: 10.1136/bmjopen-2014-004877.

10. Gyimah, A.A., Nakua, E.K., Owusu-Dabo, E. and Otupiri, E. (2015). Fertility Preferences of Women Living with HIV in the Kumasi Metropolis, Ghana. Afr J Reprod Health, 19 (2): 124-132.

11. Nakua, E., Otupiri, E., Owusu-Dabo, E., Dzomeku, V., Otu-Danquah, K. and Anderson, M. (2015). Prevalence of refractive errors among junior high school students in the Ejisu Juaben municipality of Ghana. Journal of Science and Technology (Ghana), 35:52-62.

12.  Owusu, I., Aryee, C., Owiredu, W., Osei-Yeboah, J., Owusu-Dabo, E. and Laing, E. (2015). Analysis of atherogenic and anthropometric profiles of normotensive and hypertensive Ghanaians in the Kumasi metropolis. British Journal of Medicine and Medical Research, 7:378-397.

13.  Garms, R., Badu, K., Owusu-Dabo, E., Baffour-Awuah, S., Adjei, O., Debrah, A.Y., Nagel, M., Biritwum, N.K., Gankpala, L., Post, R.J. and Kruppa, TF. (2015). Assessments of the transmission of Onchocerca volvulus by Simulium sanctipauli in the Upper Denkyira District, Ghana, and the intermittent disappearance of the vector. Parasitol Res, 114: 1129-1137.

14.  Sothmann, P., Krumkamp, R., Kreuels, B., Sarpong, N., Frank, C., Ehlkes, L., Fobil, J., Gyau, K., Jaeger, A., Bosu, B., Marks, F., Owusu-Dabo, E., Salzberger, B. and May, J. (2015). Urbanicity and paediatric bactaraemia in Ghana- A case-control study within a rural-urban transition zone. PLos One, 10(9).  e0139433.doi: 10.1371/journal.pone.0139433

15.  Nakua, E.K., Sevugu, J.T., Dzomeku, V.M., Otupiri, E., Lipkovich, H.R. and Owusu-Dabo, E. (2015). Home birth without skilled attendants despite millennium villages project intervention in Ghana: insight from a survey of women’s perceptions of skilled obstetric care. BMC Pregnancy Childbirth, 15:243. doi: 10.1186/s12884-015-0674-1.

16.  Japiong, K.B., Asiamah, G., Owusu-Dabo, E., Donkor, P., Stewart, B., Ebel, B.E. and Mock, C.N. (2015). Availability of resources for emergency care at a second-level hospital in Ghana: A mixed methods assessment. African Journal of Emergency Medicine, Doi: http://dx.doi.org/10.1016/j.afjem.2015.06.006

17.  Forbi, J.C., Layden, J.E., Phillips, R.O., Mora, N., Xia, G.L., Campo, D.S., Purdy, M.A., Dimitrova, Z.E., Owusu, D.O., Punkova, L.T., Skums, P., Owusu-Ofori, S., Sarfo, F.S., Vaughan, G., Roh, H., Opare-Sem, O.K., Cooper, R.S. and Khudyakov, YE. (2015). Next-generation sequencing reveals frequent opportunities for exposure to Hepatitis C virus in Ghana. PLoS One, 10(12):e0145530. doi: 10.1371/journal.pone.0145530.

18.  Niang, F., Sarfo, F.S., Frimpong, M., Guenin-Macé, L., Wansbrough-Jones, M., Stinear, T., Phillips, R.O. and Demangel, C. (2015).  Metabolomic profiles delineate mycolactone signature in Buruli ulcer disease. Sci Rep., 5:17693. doi: 10.1038/srep17693.

19.  Sarfo, F.S., Eberhardt, K.A., Dompreh, A., Kuffour, E.O., Soltau, M., Schachscheider, M., Drexler, J.F., Eis-Hübinger, A.M., Häussinger, D., Oteng-Seifah, E.E., Bedu-Addo, G., Phillips, R.O., Norman, B., Burchard, G. and Feldt, T. (2015). Helicobacter pylori infection is associated with higher CD4 T cell counts and lower HIV-1 viral loads in ART-naïve HIV-Positive Patients in Ghana. PLoS One, 10(11):e0143388. doi: 10.1371/journal.pone.0143388.

20.   Beissner, M., Phillips, R.O., Battke, F., Bauer, M., Badziklou, K,, Sarfo, F.S. Maman, I., Rhomberg, A., Piten, E., Frimpong, M., Huber, K.L., Symank, D., Jansson, M., Wiedemann, F.X., Banla Kere, A., Herbinger, K.H., Löscher, T. and Bretzel, G. (2015). Loop-mediated isothermal amplification for Laboratory confirmation of Buruli ulcer disease-towards a Point-of-Care Test. PLoS Negl Trop Dis., 9(11):e0004219. doi: 10.1371/journal.pntd.0004219.

21.  de Zeeuw, J., Alferink, M., Barogui, Y.T., Sopoh, G., Phillips, R.O., van der Werf, T.S., Loth, S., Molenbuur, B., Plantinga, M., Ranchor, A.V. and Stienstra, Y. (2015). Assessment and treatment of pain during treatment of Buruli ulcer. PLoS Negl Trop Dis., 9(9):e0004076. doi: 10.1371/journal.pntd.0004076.

22.  Eberhardt, K.A., Sarfo, F.S., Dompreh, A., Kuffour, E.O., Geldmacher, C., Soltau, M., Schachscheider, M., Drexler, J.F., Eis-Hübinger, A.M., Häussinger, D., Bedu-Addo, G., Phillips, R.O., Norman, B., Burchard, G.D. and Feldt, T. (2015). Helicobacter pylori co-infection Is associated with decreased markers of immune activation in ART-naive HIV-Positive and in HIV-Negative individuals in Ghana. Clin Infect Dis., 61(10): 1615-23.

23.  Alferink, M., de Zeeuw. J., Sopoh, G., Agossadou, C., Abass, K.M., Phillips, R.O., Loth, S., Jutten, E., Barogui, Y.T., Stewart, R.E., van der Werf, T.S., Stienstra, Y. and Ranchor, A.V. (2015). Pain associated with wound care treatment among Buruli ulcer patients from Ghana and Benin. PLoS One, 10(6):e0119926. doi: 10.1371/journal.pone.0119926.

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31.  Arndts, K., Klarmann-Schulz, U., Batsa, L., Debrah, A.Y., Epp, C., Fimmers, R., Specht, S., Layland, L.E. and Hoerauf, A. (2015). Reductions in microfilaridermia by repeated ivermectin treatment are associated with lower Plasmodium-specific Th17 immune responses in Onchocerca volvulus-infected individuals. Parasit Vectors, 8:184. doi: 10.1186/s13071-015-0786-5.

32.  Quintana, J.F., Makepeace, B.L., Babayan, S.A., Ivens, A., Pfarr, K.M., Blaxter, M., Debrah, A., Wanji, S., Ngangyung, H.F., Bah, G.S., Tanya, V.N., Taylor, D.W., Hoerauf, A. and Buck, A.H. (2015). Extracellular Onchocerca-derived small RNAs in host nodules and blood. Parasit Vectors, 8:58. doi: 10.1186/s13071-015-0656-1.

33.  Katawa, G., Layland, L.E., Debrah, A.Y., von Horn, C., Batsa, L., Kwarteng, A., Arriens, S., Taylor, D., Specht, S., Hoerauf, A., and Adjobimey, T. (2015). Hyperreactive onchocerciasis is characterized by a combination of Th17-Th2 immune responses and reduced regulatory T cells. PLoS Negl Trop Dis, 9(1):e3414. doi: 10.1371/journal.pntd.0003414.

34.  Rolling, T., Agbenyega, T., Krishna, S., Kremsner, P.G. and Cramer, J.P. (2015). Delayed haemolysis after artesunate treatment of severe malaria – review of the literature and perspective. Travel Med Infect Dis., 13(2): 143-9.

35.  Annan, A., Ebach, F., Corman, V.M., Krumkamp, R., Adu-Sarkodie, Y., Eis-Hübinger, A.M., Kruppa, T., Simon, A., May, J., Evans, J., Drosten, C. and Drexler, JF. (2015). Similar Virus Spectra and Seasonality in Paediatric Patients with Acute Respiratory Disease, Ghana and Germany. Clin Microbiol Infect, pii: S1198-743X(15)00980-5. doi: 10.1016/j.cmi.2015.11.002.

36.  Frickmann, H., Dekker, D., Schwarz, N.G., Hahn, A., Boahen, K., Sarpong, N., Adu-Sarkodie, Y., Halbgewachs, E., Marks, F., von Kalckreuth, V., Poppert, S., Loderstaedt, U., May, J. and Hagen, R.M. (2015). 16S rRNA Gene Sequence-Based Identification of Bacteria in Automatically Incubated Blood Culture Materials from Tropical Sub-Saharan Africa. PLoS One, 10(8):e0135923. doi: 10.1371/journal.pone.0135923.

37.  Krumkamp, R., Sarpong, N., Schwarz, N.G., Adlkofer, J., Loag, W., Eibach, D., Hagen, R.M., Adu-Sarkodie, Y., Tannich, E. and May, J. (2015). Correction: Gastrointestinal infections and diarrheal disease in Ghanaian infants and children: an outpatient case-control study. PLoS Negl Trop Dis., 9(4):e0003728. doi: 10.1371/journal.pntd.0003728.

38.  Nielsen, M.V., Amemasor, S., Agyekum, A., Loag, W., Marks, F., Sarpong, N., Dekker, D., Adu-Sarkodie, Y. and May, J. (2015). Clinical indicators for bacterial co-infection in Ghanaian children with P. falciparum infection. PLoS One, 10(4):e0122139. doi: 10.1371/journal.pone.0122139.

39.  Dekker, D.M., Krumkamp, R., Sarpong, N., Frickmann, H., Boahen, K.G., Frimpong. M., Asare, R., Larbi, R., Hagen, R.M., Poppert, S., Rabsch, W., Marks, F., Adu-Sarkodie, Y. and May, J. (2015). Drinking water from dug wells in rural Ghana–salmonella contamination, environmental factors, and genotypes. Int J Environ Res Public Health, 12(4): 3535-46.

40.  Eibach D, Krumkamp R, Al-Emran HM, Sarpong N, Hagen RM, Adu-Sarkodie Y, Tannich E, May J. (2015). Molecular characterization of Cryptosporidium spp. among children in rural Ghana. PLoS Negl Trop Dis, 9(3):e0003551. doi: 10.1371/journal.pntd.0003551.

41.  Krumkamp, R., Sarpong, N., Schwarz, N.G., Adlkofer, J., Loag, W., Eibach, D., Hagen, R.M., Adu-Sarkodie, Y., Tannich, E. and May, J. (2015). Gastrointestinal infections and diarrheal disease in Ghanaian infants and children: an outpatient case-control study. PLoS Negl Trop Dis., 9(3):e0003568. doi: 10.1371/journal.pntd.0003568. eCollection 2015 Mar. Erratum in: PLoS Negl Trop Dis, 9(4):e0003728. Adelkofer, Julia [corrected to Adlkofer, Julia].

42.  Annan, A.A., Kruppa, T.F., Adjei, O. and Garms, R. (2015). Palp ratio as a field identification tool for two members of the Anopheles gambiae complex in Ghana (A. melas and A. gambiae). Parasit Vectors, 8:295. doi: 10.1186/s13071-015-0913-3.

43.  Annan, A., Ebach, F., Corman, V.M., Krumkamp, R., Adu-Sarkodie, Y., Eis-Hübinger, A.M., Kruppa, T., Simon, A., May, J., Evans, J., Drosten, C. and Drexler, J.F. (2015). Similar virus spectra and seasonality in Paediatric Patients with Acute Respiratory Disease, Ghana and Germany. Clin Microbiol Infect, pii: S1198-743X(15)00980-5. doi: 10.1016/j.cmi.2015.11.002.

44.  Junglen, S., Marklewitz, M., Zirkel, F., Wollny, R., Meyer, B., Heidemann, H., Metzger, S., Annan, A., Dei, D., Leendertz, F.H., Oppong, S. and Drosten, C. (2015). No Evidence of Gouléako and Herbert Virus Infections in Pigs, Côte d’Ivoire and Ghana. Emerg Infect Dis., 21(12): 2190-3.

45.  Corman, V.M., Baldwin, H.J., Tateno, A.F., Zerbinati, R.M., Annan, A., Owusu, M., Nkrumah, E.E., Maganga, G.D., Oppong, S., Adu-Sarkodie, Y., Vallo, P., da Silva Filho, L.V., Leroy, E.M., Thiel, V., van der Hoek, L., Poon, L.L., Tschapka, M., Drosten, C. and Drexler, J.F. (2015). Evidence for an Ancestral Association of Human Coronavirus 229E with Bats. J Virol, 89(23): 11858-70.

46.  Freuling, C.M., Binger, T., Beer, M., Adu-Sarkodie, Y., Schatz, J., Fischer, M., Hanke, D., Hoffmann, B., Höper, D., Mettenleiter, T.C., Oppong, S.K., Drosten, C. and Müller, T. (2015). Lagos bat virus transmission in an Eidolon helvum bat colony, Ghana. Virus Res., 210: 42-5.

47.  Anti, P., Owusu, M., Agbenyega, O., Annan, A., Badu, E.K., Nkrumah, E.E., Tschapka, M., Oppong, S., Adu-Sarkodie, Y. and Drosten, C. (2015). Human-Bat Interactions in Rural West Africa. Emerg Infect Dis., 21(8): 1418-21.

48.  Freidl, G.S., Binger, T., Müller, M.A., de Bruin, E., van Beek, J., Corman, V.M., Rasche, A., Drexler, J.F., Sylverken, A., Oppong, S.K., Adu-Sarkodie, Y., Tschapka, M., Cottontail, V.M., Drosten, C. and Koopmans, M. (2015). Serological evidence of influenza A viruses in frugivorous bats from Africa. PLoS One, 10(5):e0127035. doi: 10.1371/journal.pone.0127035.

49.  Eckerle, I., Annan, A. and Drosten, C. (2015). Response to the letter to the editor: Barasheed et al., ‘No evidence of MERS-CoV in Ghanaian Hajj pilgrims: cautious interpretation is needed’. Trop Med Int Health, 20(8): 1123-4.

50.  Corman, V.M., Grundhoff, A., Baechlein, C., Fischer, N., Gmyl, A., Wollny, R., Dei, D., Ritz, D., Binger, T., Adankwah, E., Marfo, K.S., Annison, L., Annan, A., Adu-Sarkodie, Y., Oppong, S., Becher, P., Drosten, C. and Drexler, J.F. (2015). Highly divergent hepaciviruses from African cattle. J Virol, 89(11): 5876-82.

51.  Binger, T., Annan, A., Drexler, J.F., Müller, M.A., Kallies, R., Adankwah, E., Wollny, R., Kopp, A., Heidemann, H., Dei, D., Agya-Yao, F.C., Junglen, S., Feldt, T., Kurth, A., Oppong, S., Adu-Sarkodie, Y. and Drosten, C. (2015). A novel rhabdovirus isolated from the straw-colored fruit bat Eidolon helvum, with signs of antibodies in swine and humans. J Virol, 89(8): 4588-97.

52.  Schumak, B., Klocke, K., Kuepper, J.M., Biswas, A., Djie-Maletz, A., Limmer, A., van Rooijen, N., Mack, M., Hoerauf, A. and Dunay, I.R. (2015). Specific depletion of Ly6C(hi) inflammatory monocytes prevents immunopathology in experimental cerebral malaria. PLoS One, 10(4):e0124080. doi: 10.1371/journal.pone.0124080.

53.  Oteng, R.A., Whiteside, L.K., Rominski, S.D., Amuasi, J.H., Carter, P.M., Donkor, P. and Cunningham, R. (2015). Individual and Medical Characteristics of Adults Presenting to an Urban Emergency Department in Ghana. Ghana Med J., 49(3): 136-41.

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55.  Poyer, S., Shewchuk, T., Tougher, S., Ye, Y.; ACTwatch Group, Mann, A.G., Willey, B.A., Thomson, R., Amuasi, J.H., Ren, R., Wamukoya, M., Taylor, M., Nguah, S.B., Mberu, B., Kalolella, A., Juma, E., Festo, C., Johanes, B., Diap, G., Bruxvoort, K., Ansong, D., Hanson, K., Arnold, F. and Goodman, C. (2015). Availability and price of malaria rapid diagnostic tests in the public and private health sectors in 2011: results from 10 nationally representative cross-sectional retail surveys. Trop Med Int Health, 20(6): 744-56.

ARNTD Position

Scientific Officer
(with administrative duties)

Neglected tropical diseases (NTDs) are a group of disabling, disfiguring, and often life-threatening diseases affecting more than 1 billion people worldwide living on less than 1.25 USD a day. While the neglect has persisted at all levels, in recent years the international community has come together and declared renewed enthusiasm to control and finally eliminate NTDs. However, what is largely lacking are research experts, policy makers and communities in the regions most affected by NTDs, particularly Africa. Therefore to address the NTD burden from within, the African Research Network of NTD (ARNTD) was established to serve as a support platform for NTD experts on the continent. The ARNTD Secretariat is hosted by the Kumasi Center for Collaborative Research in Tropical Medicine (KCCR) and is searching for a Scientific Officer.

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Statement of board chair

Prof. Dr. Dr. Sir George Wireko Brobby

GW Brobbey

Prof. Dr. Dr. Sir George Wireko Brobby was born in Dunkwa-Ghana in 1942. He attended St. Augustine’s College, Cape Coast, before enrolling at the University of Marburg in West Germany from 1964 to 1973, where he was granted a special permission to study Medicine and Dentistry simultaneously on Ghana Government Scholarship. He graduated with MBChB in June 1971 and BDS in 1972 and followed this up with a double doctorial dissertation in 1972 and 1973 awarded with Magna cum laude in both Medicine and Dentistry. He obtained his Fellowship in Ear Nose and Throat, Head and Neck Surgery in 1977 at the University of Dusseldorf, West Germany and was elected Fellow of the West African College of Surgeons in 1985. Prof. Sir George has occupied many leadership positions. He became a foundation Fellow of the Ghana College of Physicians and Surgeons and was elected Vice Rector for three consecution terms by his peers, culminating in his position as current president of the postgraduate College. He served as President of the Ghana Medical Association from 1995 to 1997 and the Ghana Surgical Research Society from 1996 to 1998. He is a teacher at the undergraduate and postgraduate level and internal assessor at the West African College of Surgeons and the Ghana College of Physicians and Surgeons in his field of Ear Nose and Throat Surgery. Prof. Brobby was appointed WHO – consultant on prevention of Deafness and Hearing Impairment in 1996. He has travelled far and wide and collaborated with ENT Departments in institutions in Kenya, Zambia, Ethiopia, Tanzania, Nigeria, Sheffield, Liverpool, UK, Universities of Ulm and Dusseldorf, Germany, Cyprus, New Delhi, India, and Malta. Sir George is Associate Editor in the journal of Hearing International, Japan; and a member of the Editorial Board of the Ghana Medical Association. He is also a co-Editor of the British Medical Journal, African Edition and a member of the Advisory Board of KNUST Journal. His international experience includes his appointment as the President Initiative for Deaf Education in Commonwealth countries from 1994- 1998; Secretary General of the Pan African Federation of Otorhinolaryngological Societies (PAFOS) culminating in his election as President of PAFOS from 1999- 2004. Professor Sir George has published extensively in international journals and written a number of chapters in textbooks. He is the editor of a reference Book on Meningitis, March 2012 ISBN 978-953-51-0383-7. He was honoured with the prestigious Fellowship of the New York Academy of Sciences in 1992. As the longest serving Dean (1992 – 2002) of the School of Medical Sciences, and in recognition of his incisive role for the training of postgraduate doctors at SMS, the KNUST University Council honoured him with a Doctor of Science degree (honoris causa) in February 2010. For his contribution to medical education and the care of the deaf, Prof. Sir George was awarded another honorary doctorate from the Open International University in Sri Lanka. He was knighted by his Holiness Pope John Paul II with the Knighthood of St. Gregory the Great Pope in 2000 and was honoured with the Order of the Volta- Companion Division by the President of the Republic of Ghana at the National Award celebrations of 2007. Among his greatest achievements are the establishment of the Kumasi Hearing Assessment Centre at KATH through the magnificent generosity of the Commonwealth Society for the Deaf, which is the only centre recognized by WHO as a collaborative centre in the whole of the sub-region and the Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR) which is affiliated with the Bernhard Nocht Institute for Tropical Medicine in Hamburg Germany. This joint venture between the Kwame Nkrumah University of Science and Technology Kumasi, Ghana and the Ministry of Health, Ghana and the Bernhard Nocht, Institute for Tropical medicine, Hamburg, Germany was founded in 1997. Professor Brobby has recently been appointed as the Chairman of the Advisory Board of this centre of excellence in Tropical medicine for the period 2012 -2015.

Announcement

RODAM CONFERENCE IN GHANA

Working title: Global burden of Diabetes and Obesity: lessons from Europe and Ghana

 

Diabetes and obesity are a major global health burden. African migrants in high-income countries have been particularly affected by both obesity and diabetes. They also appear to develop diabetes at a younger age and have higher morbidity and mortality from diabetes compared with White counterparts. Obesity and diabetes are also increasing becoming a major public health and clinical burden in the sub-Saharan Africa. The reasons for rising levels of obesity and diabetes in African migrants and their compatriots living in Africa are poorly understood, but may involve rapid lifestyle changes, genetic predisposition, psychosocial stress as well as cultural perceptions and practises.

With the growing burden of obesity and diabetes and related complications among African migrants in Europe and in Africa, in 2012, European and African partners kicked start the RODAM project to assess the burden of obesity and diabetes and to unravel the potential factors contributing to the rising levels of obesity and diabetes among these populations in both Europe and Africa. The RODAM project is supported by the European Commission.

In doing so, the RODAM consortium has conducted one of the largest health assessment among African migrants namely Ghanaians living in 3 European cities (Amsterdam, Berlin & London) and Ghanaians living in rural and urban Ghana to identify important lifestyle changes, social, psychosocial, biological and epigenetic factors contributing to the high burden of obesity and diabetes and other health outcomes (http://www.rod-am.eu/).

The aim of this conference is to discuss the key findings of the RODAM study with policy makers, researchers, academics and the next generation scientists, and how the findings can be used to help develop prevention strategies and clinical management of obesity and diabetes among Ghanaian migrants and Ghanaians living in Ghana.

 

THEME: Beyond the Diabetes Epidemic in Africa: Addressing the Gaps in Diabetes Prevention and Care

Nuguchi Memorial Institute for Medical Research
Monday, 7th – Tuesday, 8th September 2015
Arrival of Delegates: Sunday, 6th September 2015
Departure of Delegates: Wednesday, 9th September 2015