Selected Publications:

  • Vivekanandan MM, Adankwah E, Aniagyei W, Acheampong I, Yeboah A, Arthur JF, Lamptey MN, Abass MK, Gawusu A, Kumbel F, Osei-Yeboah F. Plasma cytokine levels characterize disease pathogenesis and treatment response in tuberculosis patients. Infection. 2022 Jun 27

 

  • Aniagyei W, Adjei JK, Adankwah E, Seyfarth J, Mayatepek E, Berko DA, Sakyi SA, Debrah LB, Debrah AY, Hoerauf A, Owusu DO. Doxycycline treatment of Mansonella perstans infected individuals affects immune cell activation and causes long-term T-cell polarization. Clinical Infectious Diseases. 2022 Jun 3.

 

  • Adankwah, E., Arthur, R. A., Minadzi, D., Owusu, D. O., Phillips, R. O., & Jacobsen, M. (2021). Immune response against TB and non-tuberculous mycobacterial pulmonary disease. International Journal of Tuberculosis and Lung Disease, 25(3), 234–236. https://doi.org/10.5588/IJTLD.20.0678

 

  • Adankwah, E, Güler, A., Mayatepek, E., Phillips, R. O., Nausch, N., & Jacobsen, M. (2020). CD27 expression of T-cells discriminates IGRA-negative TB patients from healthy contacts in Ghana. Microbes and Infection, 22(1), 65–68. https://doi.org/10.1016/j.micinf.2019.07.003

 

  • Adankwah, Ernest, Harelimana, J. D. D., Minadzi, D., Aniagyei, W., Abass, M. K., Batsa Debrah, L., Owusu, D. O., Mayatepek, E., Phillips, R. O., & Jacobsen, M. (2021). Lower IL-7 Receptor Expression of Monocytes Impairs Antimycobacterial Effector Functions in Patients with Tuberculosis. Journal of Immunology (Baltimore, Md. : 1950), 206(10), 2430–2440. https://doi.org/10.4049/jimmunol.2001256

 

  • Adankwah E, Lundtoft C, Güler A, Franken KLMC, Ottenhoff THM, Mayatepek E, Owusu-Dabo E, Phillips RO, Nausch N, Jacobsen M. (2019). Two-Hit in vitro T-Cell stimulation detects mycobacterium tuberculosis infection in QuantiFERON negative tuberculosis patients and healthy contacts from Ghana. Frontiers in Immunology, 10(JUL), 1–12. https://doi.org/10.3389/fimmu.2019.01518

 

  • Adankwah, Ernest, Nausch, N., Minadzi, D., Abass, M. K., Franken, K. L. M. C. M. C., Ottenhoff, T. H. M. M., Mayatepek, E., Phillips, R. O., & Jacobsen, M. (2021). Interleukin-6 and Mycobacterium tuberculosis dormancy antigens improve diagnosis of The Journal of Infection, 82(2), 245–252. https://doi.org/10.1016/j.jinf.2020.11.032

 

  • Adankwah, Ernest, Seyfarth, J., Phillips, R., & Jacobsen, M. (2021). Aberrant cytokine milieu and signaling affect immune cell phenotypes and functions in tuberculosis pathology: What can we learn from this phenomenon for application to inflammatory syndromes? Cellular and Molecular Immunology, 18(April), 2062–2064. https://doi.org/10.1038/s41423-021-00695-8

 

  • Güler, A., Lopez Venegas, M., Adankwah, E., Mayatepek, E., Nausch, N., & Jacobsen, M. (2020). Suppressor of cytokine signalling 3 is crucial for interleukin-7 receptor re-expression after T-cell activation and interleukin-7 dependent proliferation. European Journal of Immunology, 50(2), 234–244. https://doi.org/10.1002/eji.201948302

 

  • Harelimana, J. D. D., Ahor, H. S., Benner, B., Hellmuth, S., Adankwah, E., Minadzi, D., Aniagyei, W., Lamptey, M. N. K., Arthur, J., Yeboah, A., Abass, M. K., Debrah, L. B., Owusu, D. O., Mayatepek, E., Seyfarth, J., Phillips, R. O., & Jacobsen, M. (2022). Cytokine-induced transient monocyte IL-7Ra expression and the serum milieu in European Journal of Immunology, 52(6), 958–969. https://doi.org/10.1002/eji.202149661

 

  • Harling, K., Adankwah, E., Güler, A., Afum-Adjei Awuah, A., Adu-Amoah, L., Mayatepek, E., Owusu-Dabo, E., Nausch, N., & Jacobsen, M. (2019). Constitutive STAT3 phosphorylation and IL-6/IL-10 co-expression are associated with impaired T-cell function in tuberculosis patients. Cellular & Molecular Immunology, 16(3), 275–287. https://doi.org/10.1038/cmi.2018.5

 

  • Vivekanandan, M. M., Adankwah, E., Aniagyei, W., Acheampong, I., Yeboah, A., Arthur, J. F., Lamptey, M. N. K., Abass, M. K., Gawusu, A., Kumbel, F., Osei-Yeboah, F., Debrah, L. B., Owusu, D. O., Debrah, A., Mayatepek, E., Seyfarth, J., Phillips, R. O., & Jacobsen, M. (2022). Plasma cytokine levels characterize disease pathogenesis and treatment response in tuberculosis patients. Infection. https://doi.org/10.1007/s15010-022-01870-3

 

  • Lundtoft, C., Seyfarth, J., Oberstrass, S., Rosenbauer, J., Baechle, C., Roden, M., Holl, R. W., Mayatepek, E., Kummer, S., Meissner, T., & Jacobsen, M. (2019). Autoimmunity risk- and protection-associated IL7RA genetic variants differentially affect soluble and membrane IL-7Rα expression. Journal of Autoimmunity, 97, 40–47. https://doi.org/10.1016/j.jaut.2018.10.003

 

  • Seyfarth, J., Förtsch, K., Ahlert, H., Laws, H.-J., Karges, B., Deenen, R., Köhrer, K., Mayatepek, E., Meissner, T., & Jacobsen, M. (2017). Dominant TNFα and impaired IL-2 cytokine profiles of CD4(+) T cells from children with type-1 diabetes. Immunology and Cell Biology, 95(7), 630–639. https://doi.org/10.1038/icb.2017.24

 

  • Seyfarth, J., Lundtoft, C., Förtsch, K., Ahlert, H., Rosenbauer, J., Baechle, C., Roden, M., Holl, R. W., Mayatepek, E., Kummer, S., Meissner, T., & Jacobsen, M. (2018). Interleukin-7 receptor α-chain haplotypes differentially affect soluble IL-7 receptor and IL-7 serum concentrations in children with type 1 diabetes. Pediatric Diabetes, 19(5), 955–962. https://doi.org/10.1111/pedi.12665

 

  • Seyfarth, J., Mütze, N., Antony Cruz, J., Kummer, S., Reinauer, C., Mayatepek, E., Meissner, T., & Jacobsen, M. (2019). CD4(+) T-Cells With High Common γ Chain Expression and Disturbed Cytokine Production Are Enriched in Children With Type-1 Diabetes. Frontiers in Immunology, 10, 820. https://doi.org/10.3389/fimmu.2019.00820

 

  • Seyfarth, J., Sarfo-Kantanka, O., Rosenbauer, J., Phillips, R. O., & Jacobsen, M. (2019). Type-1 diabetes onset age and sex differences between Ghanaian and German urban populations. In Journal of diabetes (Vol. 11, Issue 12, pp. 1002–1004). https://doi.org/10.1111/1753-0407.12978

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KCCR 25th Anniversary

Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR) is celebrating its 25th Anniversary. There will be a Symposium from the 29th to the 30th of November 2022.