Publications 2012

1. Frickmann H, Schwarz NG, Girmann M, Hagen RM, Poppert S, Crusius S, Podbielski A, Heriniaina JN, Razafindrabe T, Rakotondrainiarivelo JP, May J, Rakotozandrindrainy R. Serological survey of HIV and syphilis in pregnant women in Madagascar.Trop Med Int Health. 2013 Jan;18(1):35-9. doi: 10.1111/tmi.12007. Epub 2012 Oct 24.

2. Schwarz NG, Girmann M, Randriamampionona N, Bialonski A, Maus D, Krefis AC, Njarasoa C, Rajanalison JF, Ramandrisoa HD, Randriarison ML, May J, Schmidt-Chanasit J, Rakotozandrindrainy R. Seroprevalence of antibodies against Chikungunya, Dengue, and Rift Valley fever viruses after febrile illness outbreak, Madagascar.Emerg Infect Dis. 2012 Nov;18(11):1780-6. doi: 10.3201/eid1811.111036.

3. Drexler JF, Reber U, Muth D, Herzog P, Annan A, Ebach F, Sarpong N, Acquah S, Adlkofer J, Adu-Sarkodie Y, Panning M, Tannich E, May J, Drosten C, Eis-Hübinger AM.Human parvovirus 4 in nasal and fecal specimens from children, Ghana. Emerg Infect Dis. 2012 Oct;18(10):1650-3. doi: 10.3201/eid1810.111373.

4. May J, Drexler JF, Reber U, Sarpong N, Adjei O, Panning M, Drosten C, Eis-Hübinger AM.Human parvovirus 4 viremia in young children, Ghana. Emerg Infect Dis. 2012 Oct;18(10):1690-2. doi: 10.3201/eid1810.111836.

5. Nielsen MV, Sarpong N, Krumkamp R, Dekker D, Loag W, Amemasor S, Agyekum A, Marks F, Huenger F, Krefis AC, Hagen RM, Adu-Sarkodie Y, May J, Schwarz NG. Incidence and characteristics of bacteremia among children in Rural Ghana. PLoSOne.2012;7(9):e44063. doi: 10.1371/journal.pone.0044063. Epub 2012 Sep 10.

6. Timmann C, Thye T, Vens M, Evans J, May J, Ehmen C, Sievertsen J, Muntau B, Ruge G, Loag W, Ansong D, Antwi S, Asafo-Adjei E, Nguah SB, Kwakye KO, Akoto AO, Sylverken J, Brendel M, Schuldt K, Loley C, Franke A, Meyer CG, Agbenyega T, Ziegler A, Horstmann RD. Genome-wide association study indicates two novel resistance loci for severe malaria. Nature. 2012 Sep20;489(7416):443-6. doi: 10.1038/nature11334. Epub 2012 Aug 15.

7. Vinnemeier CD, Schwarz NG, Sarpong N, Loag W, Acquah S, Nkrumah B, Huenger F, Adu-Sarkodie Y, May J. Predictive value of fever and palmar pallor for P. falciparum parasitaemia in children from an endemic area. PLoSOne.2012;7(5):e36678. doi: 10.1371/journal.pone.0036678. Epub 2012 May 4.

8. Afrane YA, Lawson BW, Brenya R, Kruppa T, Yan G. The ecology of mosquitoes in an irrigated vegetable farm in Kumasi, Ghana: abundance, productivity and survivorship. Parasite Vectors. 2012 Oct 15;5:233. doi: 10.1186/1756-3305-5-233.

9. Maia MF, Abonuusum A, Lorenz LM, Clausen PH, Bauer B, Garms R, Kruppa T. The effect of deltamethrin-treated net fencing around cattle enclosures on outdoor-biting mosquitoes in Kumasi, Ghana. PLoSOne.2012;7(9):e45794. doi: 10.1371/journal.pone.0045794. Epub 2012 Sep 19.

10. Drexler JF, Corman VM, Müller MA, Maganga GD, Vallo P, Binger T, Gloza-Rausch F, Rasche A, Yordanov S, Seebens A, Oppong S, Adu Sarkodie Y, Pongombo C, Lukashev AN, Schmidt-Chanasit J, Stöcker A, Carneiro AJ, Erbar S, Maisner A, Fronhoffs F, Buettner R, Kalko EK, Kruppa T, Franke CR, Kallies R, Yandoko ER, Herrler G, Reusken C, Hassanin A, Krüger DH, Matthee S, Ulrich RG, Leroy EM, Drosten C. Bats host major mammalian paramyxoviruses. Nat Commun. 2012 Apr 24;3:796. doi: 10.1038/ncomms1796.

11. Mamoojee Y, Tan G, Gittins S, Sarfo S, Stephenson L, Carrington D, Bedu-Addo G, Phillips R, Appiah LT, Chadwick D. Diagnosis of treponemal co-infection in HIV-infected West Africans. Trop Med Int Health. 2012 Sep 20. doi: 10.1111/j.1365-3156.2012.03090.x. [Epub ahead of print]

12. Beissner M, Symank D, Phillips RO, Amoako YA, Awua-Boateng NY, Sarfo FS, Jansson M, Huber KL, Herbinger KH, Battke F, Löscher T, Adjei O, Bretzel G. Detection of viable Mycobacterium ulcerans in clinical samples by a novel combined 16S rRNA reverse transcriptase/IS2404 real-time qPCR assay. PLoS Negl Trop Dis. 2012;6(8):e1756. doi: 10.1371/journal.pntd.0001756. Epub 2012 Aug 28.

13. Bindt C, Appiah-Poku J, Te Bonle M, Schoppen S, Feldt T, Barkmann C, Koffi M, Baum J, Nguah SB, Tagbor H, Guo N, N’Goran E, Ehrhardt S; International CDS Study Group. Antepartum depression and anxiety associated with disability in African women: cross-sectional results from the CDS study in Ghana and Côte d’Ivoire. PLoS One. 2012;7(10):e48396. doi: 10.1371/journal.pone.0048396. Epub 2012 Oct 26.

14. Nguah SB, Feldt T, Hoffmann S, Pelletier D, Ansong D, Sylverken J, Mehrfar P, Herr J, Thiel C, Ehrhardt S, Burchard GD, Cramer JP. Cardiac function in Ghanaian children with severe malaria.Intensive Care Med. 2012 Dec;38(12):2032-41. doi: 10.1007/s00134-012-2676-z. Epub 2012 Aug 14.

15. Bonney JH, Kwame-Aryee RA, Obed S, Tamatey AA, Barnor JS, Armah NB, Oppong SA, Osei-Kwesi M. Fatal Hepatitis E viral infection in pregnant women in Ghana: a case series. BMC Res Notes. 2012 Sep 3;5:478. doi: 10.1186/1756-0500-5-478.

16. Drexler JF, Seelen A, Corman VM, Fumie Tateno A, Cottontail V, Melim Zerbinati R, Gloza-Rausch F, Klose SM, Adu-Sarkodie Y, Oppong SK, Kalko EK, Osterman A, Rasche A, Adam A, Müller MA, Ulrich RG, Leroy EM, Lukashev AN, Drosten C. Bats worldwide carry Hepatitis E virus-related viruses that form a putative novel genus within the family Hepeviridae. J Virol. 2012 Sep;86(17):9134-47. doi: 10.1128/JVI.00800-12. Epub 2012 Jun 13.

17. Kwofie TB, Anane YA, Nkrumah B, Annan A, Nguah SB, Owusu M. Respiratory viruses in children hospitalized for acute lower respiratory tract infection in Ghana. Virol J. 2012 Apr 10;9:78. doi: 10.1186/1743-422X-9-78.

18. Thye T, Owusu-Dabo E, Vannberg FO, van Crevel R, Curtis J, Sahiratmadja E, Balabanova Y, Ehmen C, Muntau B, Ruge G, Sievertsen J, Gyapong J, Nikolayevskyy V, Hill PC, Sirugo G, Drobniewski F, van de Vosse E, Newport M, Alisjahbana B, Nejentsev S, Ottenhoff TH, Hill AV, Horstmann RD, Meyer CG. Common variants at 11p13 are associated with susceptibility to tuberculosis. Nat Genet. 2012 Feb 5;44(3):257-9. doi: 10.1038/ng.1080.

19. Fendt L, Röck A, Zimmermann B, Bodner M, Thye T, Tschentscher F, Owusu-Dabo E, Göbel TM, Schneider PM, Parson W. MtDNA diversity of Ghana: a forensic and phylogeographic view. Forensic Sci Int Genet. 2012 Mar;6(2):244-9. doi: 10.1016/j.fsigen.2011.05.011. Epub 2011 Jun 30.

20. Shuaib FM, Ehiri JE, Jolly P, Zhang Q, Emusu D, Ngu J, Foushee H, Katongole D, Kirby R, Wabwire-Mangen F. Sexual violence and associated factors among women in HIV discordant and concordant relationships in Uganda. Int J Adolesc Med Health. 2012;24(2):125-33. doi: 10.1515/ijamh.2012.019. Epub 2011 Nov 29.

21. Bromfield S, Keenan J, Jolly P, McGwin G Jr. A suggested association between hypothyroidism and age-related macular degeneration. Curr Eye Res. 2012 Jun;37(6):549-52. doi: 10.3109/02713683.2011.647223.

22. Frojo GA, Rogers NG, Mazariegos M, Keenan J, Jolly P. Relationship between the nutritional status of breastfeeding Mayan mothers and their infants in Guatemala. Matern Child Nutr. 2012 Mar 28. doi: 10.1111/j.1740-8709.2012.00404.x. [Epub ahead of print]

23. Owusu M, Nguah SB, Boaitey YA, Badu-Boateng E, Abubakr AR, Lartey RA, Adu-Sarkodie Y. Aetiological agents of cerebrospinal meningitis: a retrospective study from a teaching hospital in Ghana. Ann Clin Microbiol Antimicrob. 2012 Oct 4;11:28. doi: 10.1186/1476-0711-11-28.

24. RTS,S Clinical Trials Partnership: Agnandji ST, Lell B, Fernandes JF, Abossolo BP, Methogo BG, Kabwende AL, Adegnika AA, Mordmüller B, Issifou S, Kremsner PG, Sacarlal J, Aide P, Lanaspa M, Aponte JJ, Machevo S, Acacio S, Bulo H, Sigauque B, Macete E, Alonso P, Abdulla S, Salim N, Minja R, Mpina M, Ahmed S, Ali AM, Mtoro AT, Hamad AS, Mutani P, Tanner M, Tinto H, D’Alessandro U, Sorgho H, Valea I, Bihoun B, Guiraud I, Kaboré B, Sombié O, Guiguemdé RT, Ouédraogo JB, Hamel MJ, Kariuki S, Oneko M, Odero C, Otieno K, Awino N, McMorrow M, Muturi-Kioi V, Laserson KF, Slutsker L, Otieno W, Otieno L, Otsyula N, Gondi S, Otieno A, Owira V, Oguk E, Odongo G, Woods JB, Ogutu B, Njuguna P, Chilengi R, Akoo P, Kerubo C, Maingi C,Lang T, Olotu A, Bejon P, Marsh K, Mwambingu G, Owusu-Agyei S, Asante KP, Osei-Kwakye K, Boahen O, Dosoo D, Asante I, Adjei G, Kwara E, Chandramohan D, Greenwood B, Lusingu J, Gesase S, Malabeja A, Abdul O, Mahende C, Liheluka E, Malle L, Lemnge M, Theander TG, Drakeley C, Ansong D, Agbenyega T, Adjei S, Boateng HO, Rettig T, Bawa J, Sylverken J, Sambian D, Sarfo A, Agyekum A, Martinson F, Hoffman I, Mvalo T, Kamthunzi P, Nkomo R, Tembo T, Tegha G, Tsidya M, Kilembe J, Chawinga C, Ballou WR, Cohen J, Guerra Y, Jongert E, Lapierre D, Leach A, Lievens M, Ofori-Anyinam O, Olivier A, Vekemans J, Carter T, Kaslow D, Leboulleux D, Loucq C, Radford A, Savarese B, Schellenberg D, Sillman M, Vansadia P. A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants. N Engl J Med. 2012 Dec 13;367(24):2284-95. doi: 10.1056/NEJMoa1208394. Epub 2012 Nov 9.

25. Von Seidlein L, Olaosebikan R, Hendriksen IC, Lee SJ, Adedoyin OT, Agbenyega T, Nguah SB, Bojang K, Deen JL, Evans J, Fanello CI, Gomes E, Pedro AJ, Kahabuka C, Karema C, Kivaya E, Maitland K, Mokuolu OA, Mtove G, Mwanga-Amumpaire J, Nadjm B, Nansumba M, Ngum WP, Onyamboko MA, Reyburn H, Sakulthaew T, Silamut K, Tshefu AK, Umulisa N, Gesase S, Day NP, White NJ, Dondorp AM. Predicting the clinical outcome of severe falciparum malaria in african children: findings from a large randomized trial. Clin Infect Dis. 2012 Apr;54(8):1080-90. doi: 10.1093/cid/cis034. Epub 2012 Mar 12.

26. Tougher S; ACTwatch Group, Ye Y, Amuasi JH, Kourgueni IA, Thomson R, Goodman C, Mann AG, Ren R, Willey BA, Adegoke CA, Amin A, Ansong D, Bruxvoort K, Diallo DA, Diap G, Festo C, Johanes B, Juma E, Kalolella A, Malam O, Mberu B, Ndiaye S, Nguah SB, Seydou M, Taylor M, Rueda ST, Wamukoya M, Arnold F, Hanson K. Effect of the Affordable Medicines Facility–malaria (AMFm) on the availability, price, and market share of quality-assured artemisinin-based combination therapies in seven countries: a before-and-after analysis of outlet survey data. Lancet. 2012 Dec 1;380(9857):1916-26. doi: 10.1016/S0140-6736(12)61732-2. Epub 2012 Oct 31.

27. Cook-Huynh M, Ansong D, Steckelberg RC, Boakye I, Seligman K, Appiah L, Kumar N, Amuasi JH. Prevalence of hypertension and diabetes mellitus in adults from a rural community in Ghana. Ethn Dis. 2012 Summer;22(3):347-52.

28. Conor R. Caffrey, Mark J. Taylor, Louise Ford, Achim Hoerauf, Ken Pfarr, Jeremy M. Foster, Sanjay Kumar, Barton E. Slatko Drugs and Targets to Perturb the Symbiosis of Wolbachia and Filarial Nematodes. Published Online: 23 AUG 2012DOI: 10.1002/9783527652969.ch15

29. Andrea Schiefer, Alexander Schmitz, Till F. Schäberle, Sabine Specht, Christine Lämmer, Kelly L. Johnston, Dmitry G. Vassylyev, Gabriele M. König, Achim Hoerauf and Kenneth Pfarr
Corallopyronin A Specifically Targets and Depletes Essential Obligate Wolbachia Endobacteria From Filarial Nematodes In Vivo. http://dx.doi.org/10.1016/j.chembiol.2012.11.009,

30. Hübner MP, Shi Y, Torrero MN, Mueller E, Larson D, Soloviova K, Gondorf F, Hoerauf A, KilloranJ. KE, Stocker T, Davies SJ, KV and Mitre E. Helminth Protection against Autoimmune Diabetes in Nonobese Diabetic Mice Is Independent of a Type 2 Immune Shift and Requires TGF-β. J Immunol. 2012 Jan 15;188(2):559-68. doi: 10.4049/jimmunol.1100335. Epub 2011 Dec 14.

31. MandS, Debrah AY, Klarmann U,Batsa L, Marfo-Debrekyei Y, KwartengA, Specht S,Belda-Domene A, Fimmers R, Taylor M,Adjei O, and HoeraufA, Doxycycline Improves Filarial Lymphedema Independent of Active Filarial Infection: A Randomized Controlled Trial. Clin Infect Dis. 2012 Sep;55(5):621-30. doi: 10.1093/cid/cis486. Epub 2012 May 18.

32. Arndts K, Deininger S, Specht S, Klarmann U, Mand S, Adjobimey T, 
 Debrah AY, Batsa L, Kwarteng A, Epp C, Taylor M, Adjei O, Layland LE, Hoerauf A. Elevated Adaptive Immune Responses Are Associated with Latent Infections of Wuchereria bancrofti. PLoS Negl Trop Dis. 2012;6(4):e1611. doi: 10.1371/journal.pntd.0001611. Epub 2012 Apr 3.

33. Lamb TJ, Specht S, Hoerauf A. Nematoda: Filarial Nematodes. Published Online: 10 AUG 2012DOI: 10.1002/9781118393321.ch11

34. Hussain H, Specht S, Sarite SR, Hoerauf A, Krohn K. New quinoline-5,8-dione and hydroxynaphthoquinone derivatives inhibit a chloroquine resistant Plasmodium falciparum strain. Eur J Med Chem. 2012 Aug;54:936-42. doi: 10.1016/j.ejmech.2012.06.046. Epub 2012 Jul 3.

35. Ziewer S, Hübner MP, Dubben B, Hoffmann WH, Bain O, Martin C, Hoerauf A, Specht S. Immunization with L. sigmodontis Microfilariae Reduces Peripheral Microfilaraemia after Challenge Infection by Inhibition of Filarial Embryogenesis. PLoS Negl Trop Dis. 2012;6(3):e1558. doi: 10.1371/journal.pntd.0001558. Epub 2012 Mar 6.

36. Albers A, Esum ME, Tendongfor N, Enyong P, Klarmann U, Wanji S, Hoerauf A and Pfarr K. Retarded Onchocerca volvulus L1 to L3 larval development in the Simulium damnosum vector after anti-wolbachial treatment of the human host. Parasit Vectors. 2012 Jan 11;5:12. doi: 10.1186/1756-3305-5-12.

37. Tendongfor N, Wanji S, Ngwa JC, Esum ME, Specht S, Enyong P, MatthaeiKI and Hoerauf A. The human parasite Loa loa in cytokine andcytokine receptor gene knock out BALB/c mice:survival, development and localization. Parasit Vectors. 2012 Feb 21;5:43. doi: 10.1186/1756-3305-5-43.

38. Pfarr KM, Hörauf A, König, Maria G, Specht S, Schiefer A, Schäberle TF, Schmitz A, Kehraus S. Compounds for use in the treatment of filariasis. European Patent Application EP2520293,Application Number: EP20110164963, Publication Date:11/07/2012

39. Bindt C, Appiah-Poku J, Bonle MT, Schoppen S, Feldt T, Barkmann C, Koffi M, Baum J, Nguah SB, Tagbor H, Guo N, N’Goran E, Ehrhardt S. Antepartum Depression and Anxiety Associated with Disability in African Women: Cross-Sectional Results from the CDS Study in Ghana and Côte d’Ivoire. PLoS One. 2012;7(10):e48396. doi: 10.1371/journal.pone.0048396. Epub 2012 Oct 26.